Spatial EGFR Dynamics and Metastatic Phenotypes Modulated by Upregulated EphB2 and Src Pathways in Advanced Prostate Cancer

Advanced prostate cancer is a very heterogeneous disease reflecting in diverse regulations of oncogenic signaling pathways. Aberrant spatial dynamics of epidermal growth factor receptor (EGFR) promote their dimerization and clustering, leading to constitutive activation in oncogenesis. The EphB2 and...

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Detalles Bibliográficos
Autores principales: Liu, Yen-Liang, Horning, Aaron M., Lieberman, Brandon, Kim, Mirae, Lin, Che-Kuang, Hung, Chia-Nung, Chou, Chih-Wei, Wang, Chiou-Miin, Lin, Chun-Lin, Kirma, Nameer B., Liss, Michael A., Vasisht, Rohan, Perillo, Evan P., Blocher, Katherine, Horng, Hannah, Taverna, Josephine A., Ruan, Jianhua, Yankeelov, Thomas E., Dunn, Andrew K., Huang, Tim H.-M., Yeh, Hsin-Chih, Chen, Chun-Liang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6966510/
https://www.ncbi.nlm.nih.gov/pubmed/31805710
http://dx.doi.org/10.3390/cancers11121910

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