Cargando…
The Chalcone Lonchocarpin Inhibits Wnt/β-Catenin Signaling and Suppresses Colorectal Cancer Proliferation
The deregulation of the Wnt/β-catenin signaling pathway is a central event in colorectal cancer progression, thus a promising target for drug development. Many natural compounds, such as flavonoids, have been described as Wnt/β-catenin inhibitors and consequently modulate important biological proces...
Autores principales: | Predes, Danilo, Oliveira, Luiz F. S., Ferreira, Laís S. S., Maia, Lorena A., Delou, João M. A., Faletti, Anderson, Oliveira, Igor, Amado, Nathalia G., Reis, Alice H., Fraga, Carlos A. M., Kuster, Ricardo, Mendes, Fabio A., Borges, Helena L., Abreu, Jose G. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6966512/ https://www.ncbi.nlm.nih.gov/pubmed/31817828 http://dx.doi.org/10.3390/cancers11121968 |
Ejemplares similares
-
Flavonoids and Wnt/β-Catenin Signaling: Potential Role in Colorectal Cancer Therapies
por: Amado, Nathália G., et al.
Publicado: (2014) -
Derricin and Derricidin Inhibit Wnt/β-Catenin Signaling and Suppress Colon Cancer Cell Growth In Vitro
por: Fonseca, Barbara F., et al.
Publicado: (2015) -
Therapeutic Potential of Naturally Occurring Small Molecules to Target the Wnt/β-Catenin Signaling Pathway in Colorectal Cancer
por: Oliveira, Luiz F. S., et al.
Publicado: (2022) -
Piperine suppresses the Wnt/β-catenin pathway and has anti-cancer effects on colorectal cancer cells
por: de Almeida, Gracielle C., et al.
Publicado: (2020) -
The Flavonol Quercitrin Hinders GSK3 Activity and Potentiates the Wnt/β-Catenin Signaling Pathway
por: Predes, Danilo, et al.
Publicado: (2022)