Cargando…

Mechanistic Signatures of Human Papillomavirus Insertions in Anal Squamous Cell Carcinomas

The role of human papillomavirus (HPV) in anal squamous cell carcinoma (ASCC) carcinogenesis has been clearly established, involving the expression of viral oncoproteins and optional viral DNA integration into the host genome. In this article, we describe the various mechanisms and sites of HPV DNA...

Descripción completa

Detalles Bibliográficos
Autores principales:	Morel, Adeline, Neuzillet, Cindy, Wack, Maxime, Lameiras, Sonia, Vacher, Sophie, Deloger, Marc, Servant, Nicolas, Veyer, David, Péré, Hélène, Mariani, Odette, Baulande, Sylvain, Rouzier, Roman, Kamal, Maud, El Alam, Elsy, Jeannot, Emmanuelle, Nicolas, Alain, Bièche, Ivan, Cacheux, Wulfran
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6966520/ https://www.ncbi.nlm.nih.gov/pubmed/31766658 http://dx.doi.org/10.3390/cancers11121846

Ejemplares similares

Human papilloma virus (HPV) integration signature in Cervical Cancer: identification of MACROD2 gene as HPV hot spot integration site
por: Kamal, Maud, et al.
Publicado: (2020)

Correction to: Human papilloma virus (HPV) integration signature in Cervical Cancer: identification of MACROD2 gene as HPV hot spot integration site
por: Kamal, Maud, et al.
Publicado: (2023)

Exome sequencing reveals aberrant signalling pathways as hallmark of treatment-naive anal squamous cell carcinoma
por: Cacheux, Wulfran, et al.
Publicado: (2017)

Array comparative genomic hybridization identifies high level of PI3K/Akt/mTOR pathway alterations in anal cancer recurrences
por: Cacheux, Wulfran, et al.
Publicado: (2018)

Human papilloma virus integration sites and genomic signatures in head and neck squamous cell carcinoma
por: Mainguené, Juliette, et al.
Publicado: (2022)

Prognostic Value of Fusobacterium nucleatum after Abdominoperineal Resection for Anal Squamous Cell Carcinoma
por: Hilmi, Marc, et al.
Publicado: (2022)

Episomal HPV16 responsible for aggressive and deadly metastatic anal squamous cell carcinoma evidenced in peripheral blood
por: Péré, Hélène, et al.
Publicado: (2021)

Mechanistic signatures of HPV insertions in cervical carcinomas
por: Holmes, Allyson, et al.
Publicado: (2016)

Prognostic value of serum CYFRA 21-1 1 in patients with anal canal squamous cell carcinoma treated with radio(chemo)therapy
por: Gauthé, Mathieu, et al.
Publicado: (2018)

Prospective validation in epithelial tumors of a gene expression predictor of liver metastasis derived from uveal melanoma
por: Tsantoulis, Petros, et al.
Publicado: (2019)

Mutational analysis of anal cancers demonstrates frequent PIK3CA mutations associated with poor outcome after salvage abdominoperineal resection
por: Cacheux, Wulfran, et al.
Publicado: (2016)

Arpin downregulation in breast cancer is associated with poor prognosis
por: Lomakina, Maria E, et al.
Publicado: (2016)

High Positive Correlations between ANRIL and p16-CDKN2A/p15-CDKN2B/p14-ARF Gene Cluster Overexpression in Multi-Tumor Types Suggest Deregulated Activation of an ANRIL–ARF Bidirectional Promoter
por: Drak Alsibai, Kinan, et al.
Publicado: (2019)

Prognostic value of intratumoral Fusobacterium nucleatum and association with immune-related gene expression in oral squamous cell carcinoma patients
por: Neuzillet, Cindy, et al.
Publicado: (2021)

Correction: Protein biomarkers predictive for response to anti-EGFR treatment in RAS wild-type metastatic colorectal carcinoma
por: Lièvre, Astrid, et al.
Publicado: (2018)

Protein biomarkers predictive for response to anti-EGFR treatment in RAS wild-type metastatic colorectal carcinoma
por: Lièvre, Astrid, et al.
Publicado: (2017)

Interactive analysis of single-cell epigenomic landscapes with ChromSCape
por: Prompsy, Pacôme, et al.
Publicado: (2020)

MRI-Based Radiomics Input for Prediction of 2-Year Disease Recurrence in Anal Squamous Cell Carcinoma
por: Giraud, Nicolas, et al.
Publicado: (2021)

Treatment Algorithms Based on Tumor Molecular Profiling: The Essence of Precision Medicine Trials
por: Le Tourneau, Christophe, et al.
Publicado: (2015)

Targeted next-generation sequencing identifies clinically relevant somatic mutations in a large cohort of inflammatory breast cancer
por: Liang, Xu, et al.
Publicado: (2018)

Comparison of anal cancer screening strategies including standard anoscopy, anal cytology, and HPV genotyping in HIV-positive men who have sex with men
por: Pernot, Simon, et al.
Publicado: (2018)

MMP2 as an independent prognostic stratifier in oral cavity cancers
por: Hoffmann, Caroline, et al.
Publicado: (2020)

Revisited analysis of a SHIVA01 trial cohort using functional mutational analyses successfully predicted treatment outcome
por: Kamal, Maud, et al.
Publicado: (2018)

Prognostic value of tumor mutational burden in patients with oral cavity squamous cell carcinoma treated with upfront surgery
por: Moreira, A., et al.
Publicado: (2021)

High Prevalence of Anal Oncogenic Human Papillomavirus Infection in Young Men Who Have Sex with Men Living in Bamako, Mali
por: Koyalta, Donato, et al.
Publicado: (2021)

MED12 mutations in breast phyllodes tumors: evidence of temporal tumoral heterogeneity and identification of associated critical signaling pathways
por: Laé, Marick, et al.
Publicado: (2016)

Sequential SARS-CoV-2 IgG assays as confirmatory strategy to confirm equivocal results: Hospital-wide antibody screening in 3,569 staff health care workers in Paris
por: Péré, Hélène, et al.
Publicado: (2020)

De Novo ESR1 Hotspot Mutation in a Patient With Endometrial Cancer Treated With an Aromatase Inhibitor
por: Morel, Adeline, et al.
Publicado: (2019)

Correction: High Prevalence of Anal Oncogenic Human Papillomavirus Infection in Young Men Who Have Sex with Men Living in Bamako, Mali
por: Koyalta, Donato, et al.
Publicado: (2021)

Identification of a large intra-exonic deletion in BRCA2 exon 18 in a pancreatic ductal adenocarcinoma
por: Debbabi, Inès, et al.
Publicado: (2023)

Limited Sensitivity of Circulating Tumor DNA Detection by Droplet Digital PCR in Non-Metastatic Operable Gastric Cancer Patients
por: Cabel, Luc, et al.
Publicado: (2019)

No SARS-CoV-2 reinfection among staff health-care workers: Prospective hospital-wide screening during the first and second waves in Paris
por: Wack, Maxime, et al.
Publicado: (2021)

A Naive Lung Adenocarcinoma Harboring G1269A ALK Resistance Mutation
por: Trabelsi-Grati, Olfa, et al.
Publicado: (2020)

Biomarkers of cetuximab resistance in patients with head and neck squamous cell carcinoma
por: Leblanc, Olivia, et al.
Publicado: (2020)

High Prevalence of Anal and Oral High-Risk Human Papillomavirus in Human Immunodeficiency Virus–Uninfected French Men Who Have Sex With Men and Use Preexposure Prophylaxis
por: Mboumba Bouassa, Ralph-Sydney, et al.
Publicado: (2019)

Altered Expression of Three EGFR Posttranslational Regulators MDGI, MIG6, and EIG121 in Invasive Breast Carcinomas
por: Meseure, Didier, et al.
Publicado: (2020)

ERBB2 mutations associated with solid variant of high-grade invasive lobular breast carcinomas
por: Deniziaut, Gabrielle, et al.
Publicado: (2016)

Unusual and unique distribution of anal high-risk human papillomavirus (HR-HPV) among men who have sex with men living in the Central African Republic
por: Mboumba Bouassa, Ralph-Sydney, et al.
Publicado: (2018)

A computational method for prioritizing targeted therapies in precision oncology: performance analysis in the SHIVA01 trial
por: Petak, Istvan, et al.
Publicado: (2021)

Combination of COX-2 expression and PIK3CA mutation as prognostic and predictive markers for celecoxib treatment in breast cancer
por: Tury, Sandrine, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_tkeboohq1ep5bpmisg8vfc8cp0