The Syk Kinase Promotes Mammary Epithelial Integrity and Inhibits Breast Cancer Invasion by Stabilizing the E-Cadherin/Catenin Complex

While first discovered in immunoreceptor signaling, the Syk protein kinase behaves as a tumor and metastasis suppressor in epithelial cells. Its reduced expression in breast and other carcinomas is correlated with decreased survival and increased metastasis risk, but its action mechanism remains lar...

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Detalles Bibliográficos
Autores principales: Kassouf, Toufic, Larive, Romain Maxime, Morel, Anne, Urbach, Serge, Bettache, Nadir, Marcial Medina, Ma Cleofas, Mèrezègue, Fabrice, Freiss, Gilles, Peter, Marion, Boissière-Michot, Florence, Solassol, Jérôme, Montcourrier, Philippe, Coopman, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6966528/
https://www.ncbi.nlm.nih.gov/pubmed/31817924
http://dx.doi.org/10.3390/cancers11121974

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