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Combing the Cancer Genome for Novel Kinase Drivers and New Therapeutic Targets
Protein kinases are critical regulators of signaling cascades that control cellular proliferation, growth, survival, metabolism, migration, and invasion. Deregulation of kinase activity can lead to aberrant regulation of biological processes and to the onset of diseases, including cancer. In this re...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6966563/ https://www.ncbi.nlm.nih.gov/pubmed/31817861 http://dx.doi.org/10.3390/cancers11121972 |