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Combing the Cancer Genome for Novel Kinase Drivers and New Therapeutic Targets

Protein kinases are critical regulators of signaling cascades that control cellular proliferation, growth, survival, metabolism, migration, and invasion. Deregulation of kinase activity can lead to aberrant regulation of biological processes and to the onset of diseases, including cancer. In this re...

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Detalles Bibliográficos
Autores principales: Torres-Ayuso, Pedro, Brognard, John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6966563/
https://www.ncbi.nlm.nih.gov/pubmed/31817861
http://dx.doi.org/10.3390/cancers11121972