Cargando…
Combing the Cancer Genome for Novel Kinase Drivers and New Therapeutic Targets
Protein kinases are critical regulators of signaling cascades that control cellular proliferation, growth, survival, metabolism, migration, and invasion. Deregulation of kinase activity can lead to aberrant regulation of biological processes and to the onset of diseases, including cancer. In this re...
Autores principales: | Torres-Ayuso, Pedro, Brognard, John |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6966563/ https://www.ncbi.nlm.nih.gov/pubmed/31817861 http://dx.doi.org/10.3390/cancers11121972 |
Ejemplares similares
-
Degraders: The Ultimate Weapon Against Amplified Driver Kinases in Cancer
por: Torres-Ayuso, Pedro, et al.
Publicado: (2022) -
New Therapeutic Opportunities for the Treatment of Squamous Cell Carcinomas: A Focus on Novel Driver Kinases
por: Bensen, Ryan, et al.
Publicado: (2021) -
Orange is the new black: Kinases are the new master regulators of tumor suppression
por: An, Elvira, et al.
Publicado: (2018) -
Druggable Drivers of Lung Cancer
por: Fawdar, Shameem, et al.
Publicado: (2013) -
Signaling pathway screening platforms are an efficient approach to identify therapeutic targets in cancers that lack known driver mutations: a case report for a cancer of unknown primary origin
por: Torres-Ayuso, Pedro, et al.
Publicado: (2018)