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JAK/STAT-Activating Genomic Alterations Are a Hallmark of T-PLL

T-cell prolymphocytic leukemia (T-PLL) is a rare and poor-prognostic mature T-cell leukemia. Recent studies detected genomic aberrations affecting JAK and STAT genes in T-PLL. Due to the limited number of primary patient samples available, genomic analyses of the JAK/STAT pathway have been performed...

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Detalles Bibliográficos
Autores principales: Wahnschaffe, Linus, Braun, Till, Timonen, Sanna, Giri, Anil K., Schrader, Alexandra, Wagle, Prerana, Almusa, Henrikki, Johansson, Patricia, Bellanger, Dorine, López, Cristina, Haferlach, Claudia, Stern, Marc-Henri, Dürig, Jan, Siebert, Reiner, Mustjoki, Satu, Aittokallio, Tero, Herling, Marco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6966610/
https://www.ncbi.nlm.nih.gov/pubmed/31766351
http://dx.doi.org/10.3390/cancers11121833

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