Cargando…

Dissecting the Anticancer Mechanism of Trifluoperazine on Pancreatic Ductal Adenocarcinoma

Pancreatic ductal adenocarcinoma (PDAC) is one of the most aggressive cancers with almost no curative chemotherapeutic treatment. Besides the development of new compounds, repurposing of approved drugs to treat cancer, alone or in combination, has become an attractive strategy, showing many therapeu...

Descripción completa

Detalles Bibliográficos
Autores principales:	Huang, Can, Lan, Wenjun, Fraunhoffer, Nicolas, Meilerman, Analía, Iovanna, Juan, Santofimia-Castaño, Patricia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6966621/ https://www.ncbi.nlm.nih.gov/pubmed/31769431 http://dx.doi.org/10.3390/cancers11121869

Ejemplares similares

Limitation and challenges in using pancreatic cancer‐derived organoids as a preclinical tool
por: Fraunhoffer, Nicolas A., et al.
Publicado: (2022)

Inhibition of glucuronidation in pancreatic cancer improves gemcitabine anticancer activity
por: Fraunhoffer, Nicolas Alejandro, et al.
Publicado: (2022)

Targeting Fibrosis: The Bridge That Connects Pancreatitis and Pancreatic Cancer
por: Huang, Can, et al.
Publicado: (2021)

Multi-omics data integration and modeling unravels new mechanisms for pancreatic cancer and improves prognostic prediction
por: Fraunhoffer, Nicolas A., et al.
Publicado: (2022)

NUPR1: A Critical Regulator of the Antioxidant System
por: Huang, Can, et al.
Publicado: (2021)

Targeting the Stress-Induced Protein NUPR1 to Treat Pancreatic Adenocarcinoma
por: Santofimia-Castaño, Patricia, et al.
Publicado: (2019)

Pancreatic ductal adenocarcinoma ubiquitination profiling reveals specific prognostic and theranostic markers
por: El Kaoutari, Abdessamad, et al.
Publicado: (2023)

Exploring the Complementarity of Pancreatic Ductal Adenocarcinoma Preclinical Models
por: Hoare, Owen, et al.
Publicado: (2021)

E2F signature is predictive for the pancreatic adenocarcinoma clinical outcome and sensitivity to E2F inhibitors, but not for the response to cytotoxic-based treatments
por: Lan, Wenjun, et al.
Publicado: (2018)

Priming therapy by targeting enhancer-initiated pathways in patient-derived pancreatic cancer cells
por: Fraunhoffer, Nicolas A., et al.
Publicado: (2023)

Identification of germ cell-specific VASA and IFITM3 proteins in human ovarian endometriosis
por: Fraunhoffer, Nicolas A., et al.
Publicado: (2015)

Trifluoperazine-Induced Angioedema
por: Osman, Mugtaba, et al.
Publicado: (2014)

Expression of POU2F3 Transcription Factor Control Inflammation, Immunological Recruitment and Metastasis of Pancreatic Cancer in Mice
por: Bintz, Jennifer, et al.
Publicado: (2020)

Pseudo-tetanus following trifluoperazine.
por: Shorten, G. D., et al.
Publicado: (1990)

Trifluoperazine-Induced Cholestatic Jaundice
por: Sharifi, Vandad, et al.
Publicado: (2010)

Hypokalemia with Trifluoperazine at Therapeutic Dose
por: Rehman, Sajjadur, et al.
Publicado: (2017)

Dissecting cell-type-specific metabolism in pancreatic ductal adenocarcinoma
por: Lau, Allison N, et al.
Publicado: (2020)

Long-term apoptosis-related protein expression in the diabetic mouse ovary
por: Fraunhoffer, Nicolas A., et al.
Publicado: (2018)

Metabolomic profiling of pancreatic adenocarcinoma reveals key features driving clinical outcome and drug resistance
por: Kaoutari, Abdessamad El, et al.
Publicado: (2021)

Inhibition of dengue virus infection by trifluoperazine
por: Piccini, Luana E., et al.
Publicado: (2022)

Pancreatic Ductal Adenocarcinoma: A Strong Imbalance of Good and Bad Immunological Cops in the Tumor Microenvironment
por: Foucher, Etienne D., et al.
Publicado: (2018)

Induction of Apoptosis in Human Pancreatic Cancer Stem Cells by the Endoplasmic Reticulum-Targeted Alkylphospholipid Analog Edelfosine and Potentiation by Autophagy Inhibition
por: Gajate, Consuelo, et al.
Publicado: (2021)

Syndecans and Pancreatic Ductal Adenocarcinoma
por: Betriu, Nausika, et al.
Publicado: (2021)

Multiphasic Heterogeneity of Fibroblasts in the Microenvironment of Pancreatic Ductal Adenocarcinoma: Dissection and the Sum of the Dynamics
por: Ijichi, Hideaki
Publicado: (2022)

Inactivation of NUPR1 promotes cell death by coupling ER-stress responses with necrosis
por: Santofimia-Castaño, Patricia, et al.
Publicado: (2018)

Design of Inhibitors of the Intrinsically Disordered Protein NUPR1: Balance between Drug Affinity and Target Function
por: Rizzuti, Bruno, et al.
Publicado: (2021)

Cadherin-1 and cadherin-3 cooperation determines the aggressiveness of pancreatic ductal adenocarcinoma
por: Siret, Carole, et al.
Publicado: (2018)

A glycosyltransferase gene signature to detect pancreatic ductal adenocarcinoma patients with poor prognosis
por: Mohamed Abd-El-Halim, Yousra, et al.
Publicado: (2021)

Deciphering CHFR Role in Pancreatic Ductal Adenocarcinoma
por: González-Borja, Iranzu, et al.
Publicado: (2021)

A pancreatic ductal adenocarcinoma subpopulation is sensitive to FK866, an inhibitor of NAMPT
por: Barraud, Marine, et al.
Publicado: (2016)

Anticancer effects of herbal medicines in pancreatic ductal adenocarcinoma through modulation of steroid hormone response proteins
por: Zhang, Zhiyi, et al.
Publicado: (2022)

Mimics of pancreatic ductal adenocarcinoma
por: Al-Hawary, Mahmoud M., et al.
Publicado: (2013)

Pancreatic ductal adenocarcinoma staging
por: Al-Hawary, Mahmoud M., et al.
Publicado: (2013)

Models of pancreatic ductal adenocarcinoma
por: Dennaoui, Rayane, et al.
Publicado: (2021)

Deciphering the Crosstalk Between Myeloid-Derived Suppressor Cells and Regulatory T Cells in Pancreatic Ductal Adenocarcinoma
por: Siret, Carole, et al.
Publicado: (2020)

Modeling the mechanical stiffness of pancreatic ductal adenocarcinoma
por: Kpeglo, Delanyo, et al.
Publicado: (2022)

LDL receptor-peptide conjugate as in vivo tool for specific targeting of pancreatic ductal adenocarcinoma
por: Acier, Angélina, et al.
Publicado: (2021)

NUPR1 inhibitor ZZW-115 induces ferroptosis in a mitochondria-dependent manner
por: Huang, Can, et al.
Publicado: (2021)

Pancreatic Ductal Adenocarcinoma Associated with Autoimmune Pancreatitis
por: Pezzilli, Raffaele, et al.
Publicado: (2011)

Expression of Notch receptors and their ligands in pancreatic ductal adenocarcinoma
por: Song, Hai-Yan, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_vat3jb10b02ip77hqq2bilo9di