Analysis of the Whole-Exome Sequencing of Tumor and Circulating Tumor DNA in Metastatic Melanoma

The use of circulating tumor DNA (ctDNA) to monitor cancer progression and response to therapy has significant potential but there is only limited data on whether this technique can detect the presence of low frequency subclones that may ultimately confer therapy resistance. In this study, we sought...

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Detalles Bibliográficos
Autores principales: Diefenbach, Russell J., Lee, Jenny H., Strbenac, Dario, Yang, Jean Y. H., Menzies, Alexander M., Carlino, Matteo S., Long, Georgina V., Spillane, Andrew J., Stretch, Jonathan R., Saw, Robyn P. M., Thompson, John F., Ch’ng, Sydney, Scolyer, Richard A., Kefford, Richard F., Rizos, Helen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6966626/
https://www.ncbi.nlm.nih.gov/pubmed/31795494
http://dx.doi.org/10.3390/cancers11121905

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6966626/
https://www.ncbi.nlm.nih.gov/pubmed/31795494
http://dx.doi.org/10.3390/cancers11121905

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