Inhibition of Histone Demethylases LSD1 and UTX Regulates ERα Signaling in Breast Cancer

In breast cancer, Lysine-specific demethylase-1 (LSD1) and other lysine demethylases (KDMs), such as Lysine-specific demethylase 6A also known as Ubiquitously transcribed tetratricopeptide repeat, X chromosome (UTX), are co-expressed and co-localize with estrogen receptors (ERs), suggesting the pote...

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Detalles Bibliográficos
Autores principales: Benedetti, Rosaria, Dell’Aversana, Carmela, De Marchi, Tommaso, Rotili, Dante, Liu, Ning Qing, Novakovic, Boris, Boccella, Serena, Di Maro, Salvatore, Cosconati, Sandro, Baldi, Alfonso, Niméus, Emma, Schultz, Johan, Höglund, Urban, Maione, Sabatino, Papulino, Chiara, Chianese, Ugo, Iovino, Francesco, Federico, Antonio, Mai, Antonello, Stunnenberg, Hendrik G., Nebbioso, Angela, Altucci, Lucia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6966629/
https://www.ncbi.nlm.nih.gov/pubmed/31888209
http://dx.doi.org/10.3390/cancers11122027

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