HuR Reduces Radiation-Induced DNA Damage by Enhancing Expression of ARID1A

Tumor suppressor ARID1A, a subunit of the chromatin remodeling complex SWI/SNF, regulates cell cycle progression, interacts with the tumor suppressor TP53, and prevents genomic instability. In addition, ARID1A has been shown to foster resistance to cancer therapy. By promoting non-homologous end joi...

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Detalles Bibliográficos
Autores principales: Andrade, Daniel, Mehta, Meghna, Griffith, James, Oh, Sangphil, Corbin, Joshua, Babu, Anish, De, Supriyo, Chen, Allshine, Zhao, Yan D., Husain, Sanam, Roy, Sudeshna, Xu, Liang, Aube, Jeffrey, Janknecht, Ralf, Gorospe, Myriam, Herman, Terence, Ramesh, Rajagopal, Munshi, Anupama
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6966656/
https://www.ncbi.nlm.nih.gov/pubmed/31847141
http://dx.doi.org/10.3390/cancers11122014

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