The Hidden Story of Heterogeneous B-raf V600E Mutation Quantitative Protein Expression in Metastatic Melanoma—Association with Clinical Outcome and Tumor Phenotypes

In comparison to other human cancer types, malignant melanoma exhibits the greatest amount of heterogeneity. After DNA-based detection of the BRAF V600E mutation in melanoma patients, targeted inhibitor treatment is the current recommendation. This approach, however, does not take the abundance of t...

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Detalles Bibliográficos
Autores principales: Betancourt, Lazaro Hiram, Szasz, A. Marcell, Kuras, Magdalena, Rodriguez Murillo, Jimmy, Sugihara, Yutaka, Pla, Indira, Horvath, Zsolt, Pawłowski, Krzysztof, Rezeli, Melinda, Miharada, Kenichi, Gil, Jeovanis, Eriksson, Jonatan, Appelqvist, Roger, Miliotis, Tasso, Baldetorp, Bo, Ingvar, Christian, Olsson, Håkan, Lundgren, Lotta, Horvatovich, Peter, Welinder, Charlotte, Wieslander, Elisabet, Kwon, Ho Jeong, Malm, Johan, Nemeth, Istvan Balazs, Jönsson, Göran, Fenyö, David, Sanchez, Aniel, Marko-Varga, György
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6966659/
https://www.ncbi.nlm.nih.gov/pubmed/31835364
http://dx.doi.org/10.3390/cancers11121981

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