Cargando…
Tumour-Secreted Protein S (ProS1) Activates a Tyro3-Erk Signalling Axis and Protects Cancer Cells from Apoptosis
The TAM subfamily (Tyro3, Axl, MerTK) of receptor tyrosine kinases are implicated in several cancers, where they have been shown to support primary tumorigenesis as well as secondary resistance to cancer therapies. Relatively little is known about the oncogenic role of Tyro3, including its ligand se...
Autores principales: | Al Kafri, Nour, Hafizi, Sassan |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6966665/ https://www.ncbi.nlm.nih.gov/pubmed/31766614 http://dx.doi.org/10.3390/cancers11121843 |
Ejemplares similares
-
Galectin-3 Stimulates Tyro3 Receptor Tyrosine Kinase and Erk Signalling, Cell Survival and Migration in Human Cancer Cells
por: Al Kafri, Nour, et al.
Publicado: (2020) -
Identification of signalling pathways activated by Tyro3 that promote cell survival, proliferation and invasiveness in human cancer cells
por: Al Kafri, Nour, et al.
Publicado: (2021) -
The first laminin G-like domain of protein S is essential for binding and activation of Tyro3 receptor and intracellular signalling
por: Al Kafri, Nour, et al.
Publicado: (2022) -
The Pros1/Tyro3 axis protects against periodontitis by modulating STAT/SOCS signalling
por: Jiang, Lei, et al.
Publicado: (2019) -
TYRO3 as a molecular target for growth inhibition and apoptosis induction in bladder cancer
por: Dufour, Florent, et al.
Publicado: (2019)