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Potent Antitumor Activity of Liposomal Irinotecan in an Organoid- and CRISPR-Cas9-Based Murine Model of Gallbladder Cancer
Gallbladder cancer is associated with a dismal prognosis, and accurate in vivo models will be elemental to improve our understanding of this deadly disease and develop better treatment options. We have generated a transplantation-based murine model for gallbladder cancer that histologically mimics t...
Autores principales: | Erlangga, Zulrahman, Wolff, Katharina, Poth, Tanja, Peltzer, Alexander, Nahnsen, Sven, Spielberg, Steffi, Timrott, Kai, Woller, Norman, Kühnel, Florian, Manns, Michael P., Saborowski, Anna, Vogel, Arndt, Saborowski, Michael |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6966678/ https://www.ncbi.nlm.nih.gov/pubmed/31795490 http://dx.doi.org/10.3390/cancers11121904 |
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