Crosstalk between SHH and FGFR Signaling Pathways Controls Tissue Invasion in Medulloblastoma

In the Sonic Hedgehog (SHH) subgroup of medulloblastoma (MB), tumor initiation and progression are in part driven by smoothened (SMO) and fibroblast growth factor (FGF)-receptor (FGFR) signaling, respectively. We investigated the impact of the SMO-FGFR crosstalk on tumor growth and invasiveness in M...

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Detalles Bibliográficos
Autores principales: Neve, Anuja, Migliavacca, Jessica, Capdeville, Charles, Schönholzer, Marc Thomas, Gries, Alexandre, Ma, Min, Santhana Kumar, Karthiga, Grotzer, Michael, Baumgartner, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6966681/
https://www.ncbi.nlm.nih.gov/pubmed/31835472
http://dx.doi.org/10.3390/cancers11121985

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