Cargando…

Preoperative, biopsy‐based assessment of the tumour microenvironment in patients with primary operable colorectal cancer

The tumour microenvironment (TME) is recognised as an important prognostic characteristic and therapeutic target in patients with colorectal cancer (CRC). However, assessment generally utilises surgically resected specimens, precluding neoadjuvant targeting. The present study investigated the feasib...

Descripción completa

Detalles Bibliográficos
Autores principales:	Park, James H, van Wyk, Hester, McMillan, Donald C, Edwards, Joanne, Orange, Clare, Horgan, Paul G, Roxburgh, Campbell SD
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley & Sons, Inc. 2019
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6966701/ https://www.ncbi.nlm.nih.gov/pubmed/31486287 http://dx.doi.org/10.1002/cjp2.143

Ejemplares similares

The relationship between tumour budding, the tumour microenvironment and survival in patients with primary operable colorectal cancer
por: van Wyk, Hester C, et al.
Publicado: (2016)

Relationship between immune checkpoint proteins, tumour microenvironment characteristics, and prognosis in primary operable colorectal cancer
por: Al‐Badran, Sara SF, et al.
Publicado: (2020)

The Relationship Between Tumor Budding, Tumor Microenvironment, and Survival in Patients with Primary Operable Colorectal Cancer
por: van Wyk, Hester C., et al.
Publicado: (2019)

Mismatch repair status in patients with primary operable colorectal cancer: associations with the local and systemic tumour environment
por: Park, James H, et al.
Publicado: (2016)

Tumour invasiveness, the local and systemic environment and the basis of staging systems in colorectal cancer
por: Park, J H, et al.
Publicado: (2017)

The Impact of Preoperative Dexamethasone on the Magnitude of the Postoperative Systemic Inflammatory Response and Complications Following Surgery for Colorectal Cancer
por: McSorley, Stephen T., et al.
Publicado: (2017)

The relationship between right-sided tumour location, tumour microenvironment, systemic inflammation, adjuvant therapy and survival in patients undergoing surgery for colon and rectal cancer
por: Patel, Meera, et al.
Publicado: (2018)

Relationship between tumour PTEN/Akt/COX-2 expression, inflammatory response and survival in patients with colorectal cancer
por: Roseweir, Antonia K., et al.
Publicado: (2016)

Relationship between pre-operative glycated haemoglobin and surgical site infection in patients undergoing elective colon cancer surgery
por: Cheong, Chee Mei, et al.
Publicado: (2022)

The Glasgow Microenvironment Score and risk and site of recurrence in TNM I–III colorectal cancer
por: Alexander, P. G., et al.
Publicado: (2022)

The Glasgow Microenvironment Score associates with prognosis and adjuvant chemotherapy response in colorectal cancer
por: Alexander, Peter G., et al.
Publicado: (2020)

The impact of preoperative systemic inflammation on the efficacy of intravenous iron infusion to correct anaemia prior to surgery for colorectal cancer
por: McSorley, Stephen T., et al.
Publicado: (2020)

Determinants of emergency presentation in patients with colorectal cancer: a systematic review and meta-analysis
por: Golder, Allan M., et al.
Publicado: (2022)

CXCL8 expression is associated with advanced stage, right sidedness, and distinct histological features of colorectal cancer
por: Pennel, Kathryn AF, et al.
Publicado: (2022)

The Relationships between Body Composition and the Systemic Inflammatory Response in Patients with Primary Operable Colorectal Cancer
por: Richards, Colin H., et al.
Publicado: (2012)

The relationships between cellular components of the peritumoural inflammatory response, clinicopathological characteristics and survival in patients with primary operable colorectal cancer
por: Richards, C H, et al.
Publicado: (2012)

The relationship between cardiopulmonary exercise test variables, the systemic inflammatory response, and complications following surgery for colorectal cancer
por: McSorley, Stephen T., et al.
Publicado: (2018)

The effect of anesthesia on the magnitude of the postoperative systemic inflammatory response in patients undergoing elective surgery for colorectal cancer in the context of an enhanced recovery pathway: A prospective cohort study
por: Alhayyan, Aliah M., et al.
Publicado: (2021)

The relationship between members of the canonical NF-κB pathway, components of tumour microenvironment and survival in patients with invasive ductal breast cancer
por: Bennett, Lindsay, et al.
Publicado: (2017)

The in situ local immune response, tumour senescence and proliferation in colorectal cancer
por: Roxburgh, C S, et al.
Publicado: (2013)

The perioperative immune/inflammatory insult in cancer surgery: Time for intervention?
por: Roxburgh, Campbell S, et al.
Publicado: (2013)

The relationship between total and phosphorylated STAT1 and STAT3 tumour cell expression, components of tumour microenvironment and survival in patients with invasive ductal breast cancer
por: Gujam, Fadia J.A., et al.
Publicado: (2016)

Circulating IL-6 concentrations link tumour necrosis and systemic and local inflammatory responses in patients undergoing resection for colorectal cancer
por: Guthrie, G J K, et al.
Publicado: (2013)

Attitudes towards the use of perioperative steroids in resectional colorectal cancer surgery in the UK: A qualitative study
por: Golder, Allan M., et al.
Publicado: (2019)

Spatially Resolved Transcriptomics Deconvolutes Prognostic Histological Subgroups in Patients with Colorectal Cancer and Synchronous Liver Metastases
por: Wood, Colin S., et al.
Publicado: (2023)

Comment on ‘Tumour-infiltrating inflammation and prognosis in colorectal cancer: systematic review and meta-analysis'
por: Park, J H, et al.
Publicado: (2014)

The role of faecal calprotectin in diagnosis and staging of colorectal neoplasia: a systematic review and meta-analysis
por: Ross, Fiona A., et al.
Publicado: (2022)

The impact of aspirin, statins and ACE-inhibitors on the presentation of colorectal neoplasia in a colorectal cancer screening programme
por: Mansouri, D, et al.
Publicado: (2013)

The relationship between lymphovascular invasion and angiogenesis, hormone receptors, cell proliferation and survival in patients with primary operable invasive ductal breast cancer
por: Mohammed, Zahra MA, et al.
Publicado: (2013)

The effect of anesthesia on the postoperative systemic inflammatory response in patients undergoing surgery: A systematic review and meta-analysis
por: Alhayyan, Aliah, et al.
Publicado: (2019)

A comparison of the prognostic value of composite ratios and cumulative scores in patients with operable rectal cancer
por: Dolan, Ross D., et al.
Publicado: (2020)

Cancer and systemic inflammation: treat the tumour and treat the host
por: Roxburgh, C S D, et al.
Publicado: (2014)

Perioperative Blood Transfusion is Associated with Postoperative Systemic Inflammatory Response and Poorer Outcomes Following Surgery for Colorectal Cancer
por: McSorley, Stephen T., et al.
Publicado: (2019)

Systemic Inflammation and Outcome in 2295 Patients with Stage I–III Colorectal Cancer from Scotland and Norway: First Results from the ScotScan Colorectal Cancer Group
por: Park, James H., et al.
Publicado: (2020)

The relationship between tumour necrosis, tumour proliferation, local and systemic inflammation, microvessel density and survival in patients undergoing potentially curative resection of oesophageal adenocarcinoma
por: Dutta, S, et al.
Publicado: (2012)

A Survey of Attitudes towards the Clinical Application of Systemic Inflammation Based Prognostic Scores in Cancer
por: Watt, David G., et al.
Publicado: (2015)

The relationship between tumour budding, the tumour microenvironment and survival in patients with invasive ductal breast cancer
por: Gujam, F J A, et al.
Publicado: (2015)

Comparison of the prognostic value of longitudinal measurements of systemic inflammation in patients undergoing curative resection of colorectal cancer
por: Guthrie, G J K, et al.
Publicado: (2013)

The Neutrophil-Platelet Score (NPS) Predicts Survival in Primary Operable Colorectal Cancer and a Variety of Common Cancers
por: Watt, David G., et al.
Publicado: (2015)

ERK and p38MAPK combine to improve survival in patients with BRAF mutant colorectal cancer
por: Roseweir, Antonia K., et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_0v3jdov1sarad7ia4fsk814103