Longitudinal analysis of a secondary BRCA2 mutation using digital droplet PCR

Development of resistance to platinum and poly(ADP‐ribose) polymerase inhibitors via secondary BRCA gene mutations that restore functional homologous recombination has been observed in a number of cancer types. Here we report a case of somatic BRCA2 mutation in a patient with high grade serous ovari...

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Detalles Bibliográficos
Autores principales: Khalique, Saira, Pettitt, Stephen J, Kelly, Ger, Tunariu, Nina, Natrajan, Rachael, Banerjee, Susana, Lord, Christopher J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2019
Materias:
Brief Definitive Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6966703/
https://www.ncbi.nlm.nih.gov/pubmed/31577852
http://dx.doi.org/10.1002/cjp2.146

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