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The capsaicin receptor TRPV1 is the first line defense protecting from acute non damaging heat: a translational approach
BACKGROUND: Pain is the vital sense preventing tissue damage by harmful noxious stimuli. The capsaicin receptor TRPV1 is activated by noxious temperatures, however, acute heat pain is only marginally affected in mice after TRPV1 knockout but completely eliminated in mice lacking TRPV1 positive fiber...
Autores principales: | Rosenberger, Daniela C., Binzen, Uta, Treede, Rolf-Detlef, Greffrath, Wolfgang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6966804/ https://www.ncbi.nlm.nih.gov/pubmed/31952468 http://dx.doi.org/10.1186/s12967-019-02200-2 |
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