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USP37 Promotes Lung Cancer Cell Migration by Stabilizing Snail Protein via Deubiquitination
Snail is a prominent epithelial–mesenchymal transition (EMT) transcription factor and promotes metastasis. However, Snail protein is unstable and is quickly degraded through ubiquitination-mediated proteasome pathway. Deubiquitinases prevent Snail degradation by regulating the ubiquitination-mediate...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6967296/ https://www.ncbi.nlm.nih.gov/pubmed/31998374 http://dx.doi.org/10.3389/fgene.2019.01324 |