Cargando…

Co-transfection of hepatocyte growth factor and truncated TGF-β type II receptor inhibit scar formation

Wound scarring remains a major challenge for plastic surgeons. Transforming growth factor (TGF)-β plays a key role in the process of scar formation. Previous studies have demonstrated that truncated TGF-β type II receptor (t-TGF-βRII) is unable to continue signal transduction but is still capable of...

Descripción completa

Detalles Bibliográficos
Autores principales:	Xu, Ji-Hua, Zhao, Wan-Yi, Fang, Qing-Qing, Wang, Xiao-Feng, Zhang, Ding-Ding, Hu, Yan-Yan, Zheng, Bin, Tan, Wei-Qiang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Associação Brasileira de Divulgação Científica 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6967399/ https://www.ncbi.nlm.nih.gov/pubmed/31939600 http://dx.doi.org/10.1590/1414-431X20199144

Ejemplares similares

The compound losartan cream inhibits scar formation via TGF-β/Smad pathway
por: Zhao, Wan-Yi, et al.
Publicado: (2022)

Angiotensin-converting enzyme inhibitor reduces scar formation by inhibiting both canonical and noncanonical TGF-β1 pathways
por: Fang, Qing-Qing, et al.
Publicado: (2018)

De novo formation of the biliary system by TGFβ-mediated hepatocyte transdifferentiation
por: Schaub, Johanna R., et al.
Publicado: (2018)

TGFβ1-transfected tendon stem cells promote tendon fibrosis
por: Yu, Hong-Bin, et al.
Publicado: (2022)

Bioflavonoid Galangin Suppresses Hypertrophic Scar Formation by the TGF-β/Smad Signaling Pathway
por: Ru, Zha, et al.
Publicado: (2021)

Marked increase in tumor transfection with a truncated branched polymer
por: Xu, Songhui, et al.
Publicado: (2021)

Expression of TGF-β1/mTOR signaling pathway in pathological scar fibroblasts
por: Zhai, Xiao-Xiang, et al.
Publicado: (2017)

Potential effect of non-thermal plasma for the inhibition of scar formation: a preliminary report
por: Wang, Xiao-Feng, et al.
Publicado: (2020)

Scar wars: is TGFβ the phantom menace in scleroderma?
por: Leask, Andrew
Publicado: (2006)

Ethanol sensitizes hepatocytes for TGF-β-triggered apoptosis
por: Gaitantzi, Haristi, et al.
Publicado: (2018)

Reprogramming of Mice Primary Hepatocytes into Insulin-Producing Cells by Transfection with Multicistronic Vectors
por: Luo, Haizhao, et al.
Publicado: (2014)

Apigenin inhibits fibrous scar formation after acute spinal cord injury through TGFβ/SMADs signaling pathway
por: Jin, Zhengxin, et al.
Publicado: (2022)

Emodin alleviates hypertrophic scar formation by suppressing macrophage polarization and inhibiting the Notch and TGF-β pathways in macrophages
por: Xia, Zihuan, et al.
Publicado: (2021)

Caveolin-1 abrogates TGF-β mediated hepatocyte apoptosis
por: Meyer, C, et al.
Publicado: (2013)

TGF-β-induced hepatocyte lincRNA-p21 contributes to liver fibrosis in mice
por: Tu, Xiaolong, et al.
Publicado: (2017)

Data on the expression of PEPCK in HepG2 hepatocytes transfected with miR-195
por: Yang, Won-Mo, et al.
Publicado: (2017)

TGF-β3 modulates the inflammatory environment and reduces scar formation following vocal fold mucosal injury in rats
por: Chang, Zhen, et al.
Publicado: (2014)

Haploinsufficiency of Def Activates p53-Dependent TGFβ Signalling and Causes Scar Formation after Partial Hepatectomy
por: Zhu, Zhihui, et al.
Publicado: (2014)

Hepatocyte growth factor regulates the TGF-β1-induced proliferation, differentiation and secretory function of cardiac fibroblasts
por: YI, XIN, et al.
Publicado: (2014)

Transforming Growth Factor-β1 (TGF-β1) Induces Mouse Precartilaginous Stem Cell Proliferation through TGF-β Receptor II (TGFRII)-Akt-β-Catenin Signaling
por: Cheng, Li, et al.
Publicado: (2014)

Process of Hypertrophic Scar Formation: Expression of Eukaryotic Initiation Factor 6
por: Yang, Qing-Qing, et al.
Publicado: (2015)

Influence of hepatocyte growth factor-transfected bone marrow-derived mesenchymal stem cells towards renal fibrosis in rats
por: Xie, Mingbu, et al.
Publicado: (2019)

Role of TGF-β 1 and TGF-β Type II Receptor in Gastric Cancer
por: Park, Dong Il, et al.
Publicado: (2002)

Expression of a Truncated, Kinase-Defective TGF-β Type II Receptor in Mouse Skeletal Tissue Promotes Terminal Chondrocyte Differentiation and Osteoarthritis
por: Serra, Rosa, et al.
Publicado: (1997)

Collecting and deactivating TGF-β1 hydrogel for anti-scarring therapy in post-glaucoma filtration surgery
por: Wang, Ruiqi, et al.
Publicado: (2022)

Molecular mechanisms of uterine incision healing and scar formation
por: Sun, Qing, et al.
Publicado: (2023)

Caveolin-1 Impacts on TGF-β Regulation of Metabolic Gene Signatures in Hepatocytes
por: Han, Mei, et al.
Publicado: (2020)

MicroRNA-21-5p mediates TGF-β-regulated fibrogenic activation of spinal fibroblasts and the formation of fibrotic scars after spinal cord injury
por: Wang, Wenzhao, et al.
Publicado: (2018)

The truncated mutant HBsAg expression increases the tumorigenesis of hepatitis B virus by regulating TGF-β/Smad signaling pathway
por: Wang, Meng-Lan, et al.
Publicado: (2018)

RGMa mediates reactive astrogliosis and glial scar formation through TGFβ1/Smad2/3 signaling after stroke
por: Zhang, Rongrong, et al.
Publicado: (2018)

Halofuginone attenuates osteoarthritis by inhibition of TGF-β activity and H-type vessel formation in subchondral bone
por: Cui, Zhuang, et al.
Publicado: (2016)

Over-Expression of ATPase II Alleviates Ethanol-Induced Hepatocyte Injury in HL-7702 Cells
por: Li, Qing, et al.
Publicado: (2018)

Shikonin reduces TGF-β1-induced collagen production and contraction in hypertrophic scar-derived human skin fibroblasts
por: FAN, CHEN, et al.
Publicado: (2015)

TGF-β and Iron Differently Alter HBV Replication in Human Hepatocytes through TGF-β/BMP Signaling and Cellular MicroRNA Expression
por: Park, Sun O., et al.
Publicado: (2012)

Glucocorticoids activate TGF-β induced PAI-1 and CTGF expression in rat hepatocytes
por: Wickert, Lucia, et al.
Publicado: (2007)

TGF-β Mediated Crosstalk Between Malignant Hepatocyte and Tumor Microenvironment in Hepatocellular Carcinoma
por: Gupta, Devendra Kumar, et al.
Publicado: (2014)

Let-7 suppresses liver fibrosis by inhibiting hepatocyte apoptosis and TGF-β production
por: Song, Jiahui, et al.
Publicado: (2023)

A review of emerging physical transfection methods for CRISPR/Cas9-mediated gene editing
por: Fajrial, Apresio K., et al.
Publicado: (2020)

Comparative nucleic acid transfection efficacy in primary hepatocytes for gene silencing and functional studies
por: Park, Jae-Seung, et al.
Publicado: (2011)

Efficient transfection of Atlantic salmon primary hepatocyte cells for functional assays and gene editing
por: Datsomor, Alex K, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_7fmnrhaubb5e6svmldo7amcfe0