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Zein nanoparticles as nontoxic delivery system for maytansine in the treatment of non-small cell lung cancer
Purpose: Maytansine (DM1) is a potent anticancer drug and limited in clinical application due to its poor water solubility and toxic side effects. Zein is widely used in nano drug delivery systems due to its good biocompatibility. In this study, we prepared DM1-loaded zein nanoparticles (ZNPs) to ac...
Autores principales: | Yu, Xianglong, Wu, Huichao, Hu, Haiyan, Dong, Ziyi, Dang, Yunni, Qi, Qi, Wang, Yan, Du, Shouying, Lu, Yang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6968508/ https://www.ncbi.nlm.nih.gov/pubmed/31870183 http://dx.doi.org/10.1080/10717544.2019.1704942 |
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