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Incidental descending thoracic aortic thrombus: the conundrum of medical versus surgical therapy

Background: A mural thrombus in the descending thoracic aorta frequently leads to distal organ and acute limb ischemia, increasing overall morbidity and mortality. Early diagnosis is imperative as thrombi are usually discovered after end organ damage has taken place. The formation of a mural thrombu...

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Autores principales: Khine, Kay, Toor, Amit, Khalighi, Koroush, Krishnamurthy, Mahesh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6968514/
https://www.ncbi.nlm.nih.gov/pubmed/32002156
http://dx.doi.org/10.1080/20009666.2019.1684230
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author Khine, Kay
Toor, Amit
Khalighi, Koroush
Krishnamurthy, Mahesh
author_facet Khine, Kay
Toor, Amit
Khalighi, Koroush
Krishnamurthy, Mahesh
author_sort Khine, Kay
collection PubMed
description Background: A mural thrombus in the descending thoracic aorta frequently leads to distal organ and acute limb ischemia, increasing overall morbidity and mortality. Early diagnosis is imperative as thrombi are usually discovered after end organ damage has taken place. The formation of a mural thrombus in descending aorta has not been fully explained; however, the principle of Virchow’s triad for thrombogenesis (hypercoagulability, stasis of blood flow and endothelial injury) remains the likely pathophysiologic mechanism. Case Presentation: We present a case of a descending aortic thrombus incidentally detected on computed tomography scan in a 65-year-old female and successfully treated with anticoagulation, preventing subsequent complications. Conclusions: Suspicion for an aortic thrombus should arise when the origin is not known for acute onset distal limb or organ ischemia.
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spelling pubmed-69685142020-01-30 Incidental descending thoracic aortic thrombus: the conundrum of medical versus surgical therapy Khine, Kay Toor, Amit Khalighi, Koroush Krishnamurthy, Mahesh J Community Hosp Intern Med Perspect Case Report Background: A mural thrombus in the descending thoracic aorta frequently leads to distal organ and acute limb ischemia, increasing overall morbidity and mortality. Early diagnosis is imperative as thrombi are usually discovered after end organ damage has taken place. The formation of a mural thrombus in descending aorta has not been fully explained; however, the principle of Virchow’s triad for thrombogenesis (hypercoagulability, stasis of blood flow and endothelial injury) remains the likely pathophysiologic mechanism. Case Presentation: We present a case of a descending aortic thrombus incidentally detected on computed tomography scan in a 65-year-old female and successfully treated with anticoagulation, preventing subsequent complications. Conclusions: Suspicion for an aortic thrombus should arise when the origin is not known for acute onset distal limb or organ ischemia. Taylor & Francis 2019-12-14 /pmc/articles/PMC6968514/ /pubmed/32002156 http://dx.doi.org/10.1080/20009666.2019.1684230 Text en © 2019 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group on behalf of Greater Baltimore Medical Center. http://creativecommons.org/licenses/by-nc/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Khine, Kay
Toor, Amit
Khalighi, Koroush
Krishnamurthy, Mahesh
Incidental descending thoracic aortic thrombus: the conundrum of medical versus surgical therapy
title Incidental descending thoracic aortic thrombus: the conundrum of medical versus surgical therapy
title_full Incidental descending thoracic aortic thrombus: the conundrum of medical versus surgical therapy
title_fullStr Incidental descending thoracic aortic thrombus: the conundrum of medical versus surgical therapy
title_full_unstemmed Incidental descending thoracic aortic thrombus: the conundrum of medical versus surgical therapy
title_short Incidental descending thoracic aortic thrombus: the conundrum of medical versus surgical therapy
title_sort incidental descending thoracic aortic thrombus: the conundrum of medical versus surgical therapy
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6968514/
https://www.ncbi.nlm.nih.gov/pubmed/32002156
http://dx.doi.org/10.1080/20009666.2019.1684230
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