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The application of nanogenerators and piezoelectricity in osteogenesis

Bone is a complex organ possessing both physicomechanical and bioelectrochemical properties. In the view of Wolff’s Law, bone can respond to mechanical loading and is subsequently reinforced in the areas of stress. Piezoelectricity is one of several mechanical responses of the bone matrix that allow...

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Autores principales: Kao, Fu-Cheng, Chiu, Ping-Yeh, Tsai, Tsung-Ting, Lin, Zong-Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6968561/
https://www.ncbi.nlm.nih.gov/pubmed/32002085
http://dx.doi.org/10.1080/14686996.2019.1693880
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author Kao, Fu-Cheng
Chiu, Ping-Yeh
Tsai, Tsung-Ting
Lin, Zong-Hong
author_facet Kao, Fu-Cheng
Chiu, Ping-Yeh
Tsai, Tsung-Ting
Lin, Zong-Hong
author_sort Kao, Fu-Cheng
collection PubMed
description Bone is a complex organ possessing both physicomechanical and bioelectrochemical properties. In the view of Wolff’s Law, bone can respond to mechanical loading and is subsequently reinforced in the areas of stress. Piezoelectricity is one of several mechanical responses of the bone matrix that allows osteocytes, osteoblasts, osteoclasts, and osteoprogenitors to react to changes in their environment. The present review details how osteocytes convert external mechanical stimuli into internal bioelectrical signals and the induction of intercellular cytokines from the standpoint of piezoelectricity. In addition, this review introduces piezoelectric and triboelectric materials used as self-powered electrical generators to promote osteogenic proliferation and differentiation due to their electromechanical properties, which could promote the development of promising applications in tissue engineering and bone regeneration.
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spelling pubmed-69685612020-01-30 The application of nanogenerators and piezoelectricity in osteogenesis Kao, Fu-Cheng Chiu, Ping-Yeh Tsai, Tsung-Ting Lin, Zong-Hong Sci Technol Adv Mater Focus on Nanogenerators Bone is a complex organ possessing both physicomechanical and bioelectrochemical properties. In the view of Wolff’s Law, bone can respond to mechanical loading and is subsequently reinforced in the areas of stress. Piezoelectricity is one of several mechanical responses of the bone matrix that allows osteocytes, osteoblasts, osteoclasts, and osteoprogenitors to react to changes in their environment. The present review details how osteocytes convert external mechanical stimuli into internal bioelectrical signals and the induction of intercellular cytokines from the standpoint of piezoelectricity. In addition, this review introduces piezoelectric and triboelectric materials used as self-powered electrical generators to promote osteogenic proliferation and differentiation due to their electromechanical properties, which could promote the development of promising applications in tissue engineering and bone regeneration. Taylor & Francis 2019-11-19 /pmc/articles/PMC6968561/ /pubmed/32002085 http://dx.doi.org/10.1080/14686996.2019.1693880 Text en © 2019 The Author(s). Published by National Institute for Materials Science in partnership with Taylor & Francis Group. http://creativecommons.org/licenses/by/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Focus on Nanogenerators
Kao, Fu-Cheng
Chiu, Ping-Yeh
Tsai, Tsung-Ting
Lin, Zong-Hong
The application of nanogenerators and piezoelectricity in osteogenesis
title The application of nanogenerators and piezoelectricity in osteogenesis
title_full The application of nanogenerators and piezoelectricity in osteogenesis
title_fullStr The application of nanogenerators and piezoelectricity in osteogenesis
title_full_unstemmed The application of nanogenerators and piezoelectricity in osteogenesis
title_short The application of nanogenerators and piezoelectricity in osteogenesis
title_sort application of nanogenerators and piezoelectricity in osteogenesis
topic Focus on Nanogenerators
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6968561/
https://www.ncbi.nlm.nih.gov/pubmed/32002085
http://dx.doi.org/10.1080/14686996.2019.1693880
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