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Twenty-seven continental ancestry-informative SNP analysis of bone remains to resolve a forensic case
We employed our previously developed 27-plex ancestry-informative single nucleotide polymorphism (SNP) panel to infer the ancestral components of bone remains of a possible foreign pilot found in south-western China. For ancestry assignment of this unknown individual, we first obtained the 27-SNP ge...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6968571/ https://www.ncbi.nlm.nih.gov/pubmed/32002497 http://dx.doi.org/10.1080/20961790.2017.1306431 |
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author | Sun, Qifan Jiang, Li Zhang, Guangfeng Liu, Jing Zhao, Lei Zhao, Wenting Li, Caixia |
author_facet | Sun, Qifan Jiang, Li Zhang, Guangfeng Liu, Jing Zhao, Lei Zhao, Wenting Li, Caixia |
author_sort | Sun, Qifan |
collection | PubMed |
description | We employed our previously developed 27-plex ancestry-informative single nucleotide polymorphism (SNP) panel to infer the ancestral components of bone remains of a possible foreign pilot found in south-western China. For ancestry assignment of this unknown individual, we first obtained the 27-SNP genotype of the individual. Then, based on a reference database of 3081 individuals from 33 populations, we calculated the match probability and likelihood ratio using the self-developed software program Forensic Intelligence. Inferred ancestral components of this individual were calculated by structure at K = 3. A complete profile was obtained for the individual using our multiplexed SNP assay. The European population was within one order of magnitude of the highest likelihood. The major ancestral component of this individual was 97.6% European. |
format | Online Article Text |
id | pubmed-6968571 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | Taylor & Francis |
record_format | MEDLINE/PubMed |
spelling | pubmed-69685712020-01-30 Twenty-seven continental ancestry-informative SNP analysis of bone remains to resolve a forensic case Sun, Qifan Jiang, Li Zhang, Guangfeng Liu, Jing Zhao, Lei Zhao, Wenting Li, Caixia Forensic Sci Res Case Reports We employed our previously developed 27-plex ancestry-informative single nucleotide polymorphism (SNP) panel to infer the ancestral components of bone remains of a possible foreign pilot found in south-western China. For ancestry assignment of this unknown individual, we first obtained the 27-SNP genotype of the individual. Then, based on a reference database of 3081 individuals from 33 populations, we calculated the match probability and likelihood ratio using the self-developed software program Forensic Intelligence. Inferred ancestral components of this individual were calculated by structure at K = 3. A complete profile was obtained for the individual using our multiplexed SNP assay. The European population was within one order of magnitude of the highest likelihood. The major ancestral component of this individual was 97.6% European. Taylor & Francis 2017-05-19 /pmc/articles/PMC6968571/ /pubmed/32002497 http://dx.doi.org/10.1080/20961790.2017.1306431 Text en © 2017 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group on behalf of the Institute of Forensic Science, Ministry of Justice, People's Republic of China http://creativecommons.org/licenses/by/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case Reports Sun, Qifan Jiang, Li Zhang, Guangfeng Liu, Jing Zhao, Lei Zhao, Wenting Li, Caixia Twenty-seven continental ancestry-informative SNP analysis of bone remains to resolve a forensic case |
title | Twenty-seven continental ancestry-informative SNP analysis of bone remains to resolve a forensic case |
title_full | Twenty-seven continental ancestry-informative SNP analysis of bone remains to resolve a forensic case |
title_fullStr | Twenty-seven continental ancestry-informative SNP analysis of bone remains to resolve a forensic case |
title_full_unstemmed | Twenty-seven continental ancestry-informative SNP analysis of bone remains to resolve a forensic case |
title_short | Twenty-seven continental ancestry-informative SNP analysis of bone remains to resolve a forensic case |
title_sort | twenty-seven continental ancestry-informative snp analysis of bone remains to resolve a forensic case |
topic | Case Reports |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6968571/ https://www.ncbi.nlm.nih.gov/pubmed/32002497 http://dx.doi.org/10.1080/20961790.2017.1306431 |
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