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Twenty-seven continental ancestry-informative SNP analysis of bone remains to resolve a forensic case

We employed our previously developed 27-plex ancestry-informative single nucleotide polymorphism (SNP) panel to infer the ancestral components of bone remains of a possible foreign pilot found in south-western China. For ancestry assignment of this unknown individual, we first obtained the 27-SNP ge...

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Autores principales: Sun, Qifan, Jiang, Li, Zhang, Guangfeng, Liu, Jing, Zhao, Lei, Zhao, Wenting, Li, Caixia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6968571/
https://www.ncbi.nlm.nih.gov/pubmed/32002497
http://dx.doi.org/10.1080/20961790.2017.1306431
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author Sun, Qifan
Jiang, Li
Zhang, Guangfeng
Liu, Jing
Zhao, Lei
Zhao, Wenting
Li, Caixia
author_facet Sun, Qifan
Jiang, Li
Zhang, Guangfeng
Liu, Jing
Zhao, Lei
Zhao, Wenting
Li, Caixia
author_sort Sun, Qifan
collection PubMed
description We employed our previously developed 27-plex ancestry-informative single nucleotide polymorphism (SNP) panel to infer the ancestral components of bone remains of a possible foreign pilot found in south-western China. For ancestry assignment of this unknown individual, we first obtained the 27-SNP genotype of the individual. Then, based on a reference database of 3081 individuals from 33 populations, we calculated the match probability and likelihood ratio using the self-developed software program Forensic Intelligence. Inferred ancestral components of this individual were calculated by structure at K = 3. A complete profile was obtained for the individual using our multiplexed SNP assay. The European population was within one order of magnitude of the highest likelihood. The major ancestral component of this individual was 97.6% European.
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spelling pubmed-69685712020-01-30 Twenty-seven continental ancestry-informative SNP analysis of bone remains to resolve a forensic case Sun, Qifan Jiang, Li Zhang, Guangfeng Liu, Jing Zhao, Lei Zhao, Wenting Li, Caixia Forensic Sci Res Case Reports We employed our previously developed 27-plex ancestry-informative single nucleotide polymorphism (SNP) panel to infer the ancestral components of bone remains of a possible foreign pilot found in south-western China. For ancestry assignment of this unknown individual, we first obtained the 27-SNP genotype of the individual. Then, based on a reference database of 3081 individuals from 33 populations, we calculated the match probability and likelihood ratio using the self-developed software program Forensic Intelligence. Inferred ancestral components of this individual were calculated by structure at K = 3. A complete profile was obtained for the individual using our multiplexed SNP assay. The European population was within one order of magnitude of the highest likelihood. The major ancestral component of this individual was 97.6% European. Taylor & Francis 2017-05-19 /pmc/articles/PMC6968571/ /pubmed/32002497 http://dx.doi.org/10.1080/20961790.2017.1306431 Text en © 2017 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group on behalf of the Institute of Forensic Science, Ministry of Justice, People's Republic of China http://creativecommons.org/licenses/by/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Reports
Sun, Qifan
Jiang, Li
Zhang, Guangfeng
Liu, Jing
Zhao, Lei
Zhao, Wenting
Li, Caixia
Twenty-seven continental ancestry-informative SNP analysis of bone remains to resolve a forensic case
title Twenty-seven continental ancestry-informative SNP analysis of bone remains to resolve a forensic case
title_full Twenty-seven continental ancestry-informative SNP analysis of bone remains to resolve a forensic case
title_fullStr Twenty-seven continental ancestry-informative SNP analysis of bone remains to resolve a forensic case
title_full_unstemmed Twenty-seven continental ancestry-informative SNP analysis of bone remains to resolve a forensic case
title_short Twenty-seven continental ancestry-informative SNP analysis of bone remains to resolve a forensic case
title_sort twenty-seven continental ancestry-informative snp analysis of bone remains to resolve a forensic case
topic Case Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6968571/
https://www.ncbi.nlm.nih.gov/pubmed/32002497
http://dx.doi.org/10.1080/20961790.2017.1306431
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