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Synthesis and biological evaluation of novel (E)-N'-benzylidene hydrazides as novel c-Met inhibitors through fragment based virtual screening

C-Met plays a crucial role in the development and progression of neoplastic disease. Type II c-Met inhibitors recognise the inactive DFG-out conformation of the kinase, result in better anti-tumour effects due to synergistic effect against the other kinases. According to our previous works, an (E)-N...

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Detalles Bibliográficos
Autores principales:	Liang, Jing-wei, Li, Shi-long, Wang, Shan, Li, Wan-qiu, Meng, Fan-hao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2020
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6968643/ https://www.ncbi.nlm.nih.gov/pubmed/31902266 http://dx.doi.org/10.1080/14756366.2019.1702655

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