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Identification of cytochrome P450 isoenzymes involved in the metabolism of 23-hydroxybetulinic acid in human liver microsomes

CONTEXT: 23-Hydroxybetulinic acid (23-HBA), a major active constituent of Pulsatilla chinensis (Bunge) Regel (Ranunculaceae), exhibits potential antitumor activity. Its metabolism, however, has not yet been studied. OBJECTIVE: This study focuses on the metabolism of 23-HBA in vitro by human liver mi...

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Detalles Bibliográficos
Autores principales:	Zhou, Ying, Wen, Jinhua, Wang, Guangji
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6968681/ https://www.ncbi.nlm.nih.gov/pubmed/31868554 http://dx.doi.org/10.1080/13880209.2019.1701500

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