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Risk Factors for Colorectal Cancer in Korea: A Population-Based Retrospective Cohort Study

PURPOSE: The incidence of colorectal cancer in Korea has recently increased, making it the second most common cancer in men and the third most common cancer in women. Risk factors for colorectal cancer have been studied worldwide, but risk factors specific for the Korean population have not been est...

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Autores principales: Nam, Soomin, Choi, Yoon Jung, Kim, Dong Wook, Park, Eun-Cheol, Kang, Jung-Gu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society of Coloproctology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6968718/
https://www.ncbi.nlm.nih.gov/pubmed/31937075
http://dx.doi.org/10.3393/ac.2019.10.21
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author Nam, Soomin
Choi, Yoon Jung
Kim, Dong Wook
Park, Eun-Cheol
Kang, Jung-Gu
author_facet Nam, Soomin
Choi, Yoon Jung
Kim, Dong Wook
Park, Eun-Cheol
Kang, Jung-Gu
author_sort Nam, Soomin
collection PubMed
description PURPOSE: The incidence of colorectal cancer in Korea has recently increased, making it the second most common cancer in men and the third most common cancer in women. Risk factors for colorectal cancer have been studied worldwide, but risk factors specific for the Korean population have not been established. In this study, we investigated incidence trends and risk factors of colorectal cancer in Korea. METHODS: A total of 8,846,749 subjects were included. Colorectal cancer incidence was investigated using Korea National Health Insurance Service claim data from 2004 to 2014. Colorectal cancer diagnoses were obtained by evaluating colorectal cancer diagnostic codes and the cancer registry for cost sharing. Risk factor identification for colorectal cancer was obtained from National Health Examination data from 2004 to 2005. Cox proportional hazard model statistical analysis was used to determine risk factors of colorectal cancer. RESULTS: The incidence of colorectal cancer gradually increased from 2006 to 2014 (from 45.4/100,000 to 54.5/100,000). There was a predominance among men (1.47:1), but incidence trends were similar in both sexes. Old age, high body mass index, and no history of colonoscopy were identified as risk factors in both sexes. High fasting blood glucose, familial history of cancer, frequent alcohol intake, and current smoker were identified as risk factors, especially in men. CONCLUSION: The incidence of colorectal cancer has been increasing in Korea. Colonoscopy screening was a protective factor for colorectal cancer, and active use of colonoscopy may reduce incidence. Early diagnosis and care are important, particularly for the high-risk group.
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spelling pubmed-69687182020-01-24 Risk Factors for Colorectal Cancer in Korea: A Population-Based Retrospective Cohort Study Nam, Soomin Choi, Yoon Jung Kim, Dong Wook Park, Eun-Cheol Kang, Jung-Gu Ann Coloproctol Original Article PURPOSE: The incidence of colorectal cancer in Korea has recently increased, making it the second most common cancer in men and the third most common cancer in women. Risk factors for colorectal cancer have been studied worldwide, but risk factors specific for the Korean population have not been established. In this study, we investigated incidence trends and risk factors of colorectal cancer in Korea. METHODS: A total of 8,846,749 subjects were included. Colorectal cancer incidence was investigated using Korea National Health Insurance Service claim data from 2004 to 2014. Colorectal cancer diagnoses were obtained by evaluating colorectal cancer diagnostic codes and the cancer registry for cost sharing. Risk factor identification for colorectal cancer was obtained from National Health Examination data from 2004 to 2005. Cox proportional hazard model statistical analysis was used to determine risk factors of colorectal cancer. RESULTS: The incidence of colorectal cancer gradually increased from 2006 to 2014 (from 45.4/100,000 to 54.5/100,000). There was a predominance among men (1.47:1), but incidence trends were similar in both sexes. Old age, high body mass index, and no history of colonoscopy were identified as risk factors in both sexes. High fasting blood glucose, familial history of cancer, frequent alcohol intake, and current smoker were identified as risk factors, especially in men. CONCLUSION: The incidence of colorectal cancer has been increasing in Korea. Colonoscopy screening was a protective factor for colorectal cancer, and active use of colonoscopy may reduce incidence. Early diagnosis and care are important, particularly for the high-risk group. Korean Society of Coloproctology 2019-12 2019-11-13 /pmc/articles/PMC6968718/ /pubmed/31937075 http://dx.doi.org/10.3393/ac.2019.10.21 Text en Copyright © 2019 The Korean Society of Coloproctology This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Nam, Soomin
Choi, Yoon Jung
Kim, Dong Wook
Park, Eun-Cheol
Kang, Jung-Gu
Risk Factors for Colorectal Cancer in Korea: A Population-Based Retrospective Cohort Study
title Risk Factors for Colorectal Cancer in Korea: A Population-Based Retrospective Cohort Study
title_full Risk Factors for Colorectal Cancer in Korea: A Population-Based Retrospective Cohort Study
title_fullStr Risk Factors for Colorectal Cancer in Korea: A Population-Based Retrospective Cohort Study
title_full_unstemmed Risk Factors for Colorectal Cancer in Korea: A Population-Based Retrospective Cohort Study
title_short Risk Factors for Colorectal Cancer in Korea: A Population-Based Retrospective Cohort Study
title_sort risk factors for colorectal cancer in korea: a population-based retrospective cohort study
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6968718/
https://www.ncbi.nlm.nih.gov/pubmed/31937075
http://dx.doi.org/10.3393/ac.2019.10.21
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