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Acute Liver Failure Induces Glial Reactivity, Oxidative Stress and Impairs Brain Energy Metabolism in Rats

Acute liver failure (ALF) implies a severe and rapid liver dysfunction that leads to impaired liver metabolism and hepatic encephalopathy (HE). Recent studies have suggested that several brain alterations such as astrocytic dysfunction and energy metabolism impairment may synergistically interact, p...

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Detalles Bibliográficos
Autores principales: Guazzelli, Pedro Arend, Cittolin-Santos, Giordano Fabricio, Meira-Martins, Leo Anderson, Grings, Mateus, Nonose, Yasmine, Lazzarotto, Gabriel S., Nogara, Daniela, da Silva, Jussemara S., Fontella, Fernanda U., Wajner, Moacir, Leipnitz, Guilhian, Souza, Diogo O., de Assis, Adriano Martimbianco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6968792/
https://www.ncbi.nlm.nih.gov/pubmed/31998076
http://dx.doi.org/10.3389/fnmol.2019.00327