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Acute Liver Failure Induces Glial Reactivity, Oxidative Stress and Impairs Brain Energy Metabolism in Rats
Acute liver failure (ALF) implies a severe and rapid liver dysfunction that leads to impaired liver metabolism and hepatic encephalopathy (HE). Recent studies have suggested that several brain alterations such as astrocytic dysfunction and energy metabolism impairment may synergistically interact, p...
Autores principales: | Guazzelli, Pedro Arend, Cittolin-Santos, Giordano Fabricio, Meira-Martins, Leo Anderson, Grings, Mateus, Nonose, Yasmine, Lazzarotto, Gabriel S., Nogara, Daniela, da Silva, Jussemara S., Fontella, Fernanda U., Wajner, Moacir, Leipnitz, Guilhian, Souza, Diogo O., de Assis, Adriano Martimbianco |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6968792/ https://www.ncbi.nlm.nih.gov/pubmed/31998076 http://dx.doi.org/10.3389/fnmol.2019.00327 |
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