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Impact of anticancer chemotherapy on the extension of beta-lactamase spectrum: an example with KPC-type carbapenemase activity towards ceftazidime-avibactam

Through their action on DNA replication, anticancer chemotherapies could increase the basal mutation rate in bacteria and increase the risk of selecting antibiotic resistant mutants. We investigated the impact of several drugs on a beta-lactamase model using KPC-type carbapenemase-producing Enteroba...

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Detalles Bibliográficos
Autores principales:	Hobson, Claire Amaris, Bonacorsi, Stéphane, Hocquet, Didier, Baruchel, André, Fahd, Mony, Storme, Thomas, Tang, Raksamy, Doit, Catherine, Tenaillon, Olivier, Birgy, André
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6969056/ https://www.ncbi.nlm.nih.gov/pubmed/31953453 http://dx.doi.org/10.1038/s41598-020-57505-w

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