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TRIM25 promotes the cell survival and growth of hepatocellular carcinoma through targeting Keap1-Nrf2 pathway

Tumor cells often exhibit augmented capacity to maintain endoplasmic reticulum (ER) homeostasis under adverse conditions, yet the underlying mechanisms are not well defined. Here, through the evaluation of all human TRIM proteins, we find that TRIM25 is significantly induced upon ER stress. Upregula...

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Detalles Bibliográficos
Autores principales:	Liu, Yanfeng, Tao, Shishi, Liao, Lijuan, Li, Yang, Li, Hongchang, Li, Zhihuan, Lin, Lilong, Wan, Xiaochun, Yang, Xiaolu, Chen, Liang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6969153/ https://www.ncbi.nlm.nih.gov/pubmed/31953436 http://dx.doi.org/10.1038/s41467-019-14190-2

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