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Update on Liver Transplantation: What is New Recently?

Liver transplantation (LT) is an evolving area of medicine for the treatment of certain types of malignancies and acute and chronic liver failures. Since the topic is evolving, new literature is increasingly available. In recent years, with the emerging potent antiviral therapies, hepatitis C virus-...

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Autores principales: Tasdogan, Burcak E, Akosman, Sinan, Gurakar, Merve, Simsek, Cem, Gurakar, Ahmet
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Jaypee Brothers Medical Publishers 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6969330/
https://www.ncbi.nlm.nih.gov/pubmed/31988865
http://dx.doi.org/10.5005/jp-journals-10018-1293
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author Tasdogan, Burcak E
Akosman, Sinan
Gurakar, Merve
Simsek, Cem
Gurakar, Ahmet
author_facet Tasdogan, Burcak E
Akosman, Sinan
Gurakar, Merve
Simsek, Cem
Gurakar, Ahmet
author_sort Tasdogan, Burcak E
collection PubMed
description Liver transplantation (LT) is an evolving area of medicine for the treatment of certain types of malignancies and acute and chronic liver failures. Since the topic is evolving, new literature is increasingly available. In recent years, with the emerging potent antiviral therapies, hepatitis C virus-infected patients have successful patient and graft survival outcomes. Even human immunodeficiency virus (HIV) positive patients previously contraindicated for organ transplantation are transplanted with comparable outcomes. With increasing demand for LT, the shortage of the donor pool became the rate limiting factor in this hopeful treatment. To overcome waitlist mortality and expand the donor pool, scoring systems have been modified and organs from HIV and/or hepatitis C infected donors are now accepted, under certain circumstances. The new literature also questions the 6-month alcohol abstinence rule for the transplantation of alcoholic liver disease (ALD), in light of early transplantation results from severe alcoholic hepatitis (SAH) trials. How to cite this article: Tasdogan BE, Akosman S, et al. Update on Liver Transplantation: What is New Recently? Euroasian J Hepatogastroenterol 2019;9(1):34-39.
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spelling pubmed-69693302020-01-27 Update on Liver Transplantation: What is New Recently? Tasdogan, Burcak E Akosman, Sinan Gurakar, Merve Simsek, Cem Gurakar, Ahmet Euroasian J Hepatogastroenterol Review Article Liver transplantation (LT) is an evolving area of medicine for the treatment of certain types of malignancies and acute and chronic liver failures. Since the topic is evolving, new literature is increasingly available. In recent years, with the emerging potent antiviral therapies, hepatitis C virus-infected patients have successful patient and graft survival outcomes. Even human immunodeficiency virus (HIV) positive patients previously contraindicated for organ transplantation are transplanted with comparable outcomes. With increasing demand for LT, the shortage of the donor pool became the rate limiting factor in this hopeful treatment. To overcome waitlist mortality and expand the donor pool, scoring systems have been modified and organs from HIV and/or hepatitis C infected donors are now accepted, under certain circumstances. The new literature also questions the 6-month alcohol abstinence rule for the transplantation of alcoholic liver disease (ALD), in light of early transplantation results from severe alcoholic hepatitis (SAH) trials. How to cite this article: Tasdogan BE, Akosman S, et al. Update on Liver Transplantation: What is New Recently? Euroasian J Hepatogastroenterol 2019;9(1):34-39. Jaypee Brothers Medical Publishers 2019 /pmc/articles/PMC6969330/ /pubmed/31988865 http://dx.doi.org/10.5005/jp-journals-10018-1293 Text en Copyright © 2019; Jaypee Brothers Medical Publishers (P) Ltd. © The Author(s). 2019 Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (https://creativecommons.org/licenses/by-nc/4.0/), which permits unrestricted use, distribution, and non-commercial reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Review Article
Tasdogan, Burcak E
Akosman, Sinan
Gurakar, Merve
Simsek, Cem
Gurakar, Ahmet
Update on Liver Transplantation: What is New Recently?
title Update on Liver Transplantation: What is New Recently?
title_full Update on Liver Transplantation: What is New Recently?
title_fullStr Update on Liver Transplantation: What is New Recently?
title_full_unstemmed Update on Liver Transplantation: What is New Recently?
title_short Update on Liver Transplantation: What is New Recently?
title_sort update on liver transplantation: what is new recently?
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6969330/
https://www.ncbi.nlm.nih.gov/pubmed/31988865
http://dx.doi.org/10.5005/jp-journals-10018-1293
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