Cargando…

Genome-wide association analysis of 350 000 Caucasians from the UK Biobank identifies novel loci for asthma, hay fever and eczema

Even though heritability estimates suggest that the risk of asthma, hay fever and eczema is largely due to genetic factors, previous studies have not explained a large part of the genetics behind these diseases. In this genome-wide association study, we include 346 545 Caucasians from the UK Biobank...

Descripción completa

Detalles Bibliográficos
Autores principales:	Johansson, Åsa, Rask-Andersen, Mathias, Karlsson, Torgny, Ek, Weronica E
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2019
Materias:	Association Studies Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6969355/ https://www.ncbi.nlm.nih.gov/pubmed/31361310 http://dx.doi.org/10.1093/hmg/ddz175

Ejemplares similares

Genome-wide association study of body fat distribution identifies adiposity loci and sex-specific genetic effects
por: Rask-Andersen, Mathias, et al.
Publicado: (2019)

Gene-environment interaction study for BMI reveals interactions between genetic factors and physical activity, alcohol consumption and socioeconomic status
por: Rask-Andersen, Mathias, et al.
Publicado: (2017)

Causal effects of inflammatory protein biomarkers on inflammatory diseases
por: Ek, Weronica E., et al.
Publicado: (2021)

Improved power and precision with whole genome sequencing data in genome-wide association studies of inflammatory biomarkers
por: Höglund, Julia, et al.
Publicado: (2019)

The relative contribution of DNA methylation and genetic variants on protein biomarkers for human diseases
por: Ahsan, Muhammad, et al.
Publicado: (2017)

Gene-Based Variant Analysis of Whole-Exome Sequencing in Relation to Eosinophil Count
por: Höglund, Julia, et al.
Publicado: (2022)

Genome-wide Association Study of Estradiol Levels and the Causal Effect of Estradiol on Bone Mineral Density
por: Schmitz, Daniel, et al.
Publicado: (2021)

Investigating the Effect of Estradiol Levels on the Risk of Breast, Endometrial, and Ovarian Cancer
por: Johansson, Åsa, et al.
Publicado: (2022)

London Needs £350,000 Now
Publicado: (1920)

Geschätzt 350.000 Fälle von Long Covid
por: Facharztmagazine, Redaktion
Publicado: (2021)

Recent Advances in Allergy (Asthma, Hay Fever, Eczema, Migraine, etc.)
Publicado: (1935)

Recent Advances in Allergy. (Asthma, Hay-Fever, Eczema, Migraine, etc.)
Publicado: (1937)

Contribution of rare whole-genome sequencing variants to plasma protein levels and the missing heritability
por: Kierczak, Marcin, et al.
Publicado: (2022)

Health service use among children with and without eczema, asthma, and hay fever
por: Hammer-Helmich, Lene, et al.
Publicado: (2016)

A combined genome-wide association and molecular study of age-related hearing loss in H. sapiens
por: Liu, Wei, et al.
Publicado: (2021)

Shared genetic origin of asthma, hay fever and eczema elucidates allergic disease biology
por: Ferreira, Manuel A, et al.
Publicado: (2017)

Kidney segmentation in neck-to-knee body MRI of 40,000 UK Biobank participants
por: Langner, Taro, et al.
Publicado: (2020)

Drug Response Pharmacogenetics for 200,000 UK Biobank Participants
por: McInnes, Gregory, et al.
Publicado: (2021)

Prevalence of allergic sensitization, hay fever, eczema, and asthma in a longitudinal birth cohort
por: Owens, Louisa, et al.
Publicado: (2018)

Tracing the influence of Mediterranean climate on Southeastern Europe during the past 350,000 years
por: Obreht, Igor, et al.
Publicado: (2016)

CAUSES OF FRAILTY: GENETIC ANALYSIS IN 164,000 UK BIOBANK PARTICIPANTS
por: Atkins, Janice, et al.
Publicado: (2019)

Mental health associations with eczema, asthma and hay fever in children: a cross-sectional survey
por: Hammer-Helmich, Lene, et al.
Publicado: (2016)

The burden of asthma, hay fever and eczema in adults in 17 countries: GAN Phase I study
por: Mortimer, Kevin, et al.
Publicado: (2022)

The burden of asthma, hay fever and eczema in children in 25 countries: GAN Phase I study
por: García-Marcos, Luis, et al.
Publicado: (2022)

The association between domestic hard water and eczema in adults from the UK Biobank cohort study
por: Lopez, Diego J., et al.
Publicado: (2022)

Intakes of major food groups in China and UK: results from 100,000 adults in the China Kadoorie biobank and UK biobank
por: Papier, Keren, et al.
Publicado: (2022)

Genome-wide enrichment analysis between endometriosis and obesity-related traits reveals novel susceptibility loci
por: Rahmioglu, Nilufer, et al.
Publicado: (2015)

MAP2K3 is associated with body mass index in American Indians and Caucasians and may mediate hypothalamic inflammation
por: Bian, Li, et al.
Publicado: (2013)

The Expression of BAFF, APRIL and TWEAK Is Altered in Eczema Skin but Not in the Circulation of Atopic and Seborrheic Eczema Patients
por: Chen, Yunying, et al.
Publicado: (2011)

Personality, lifestyle and job satisfaction: causal association between neuroticism and job satisfaction using Mendelian randomisation in the UK biobank cohort
por: Rukh, Gull, et al.
Publicado: (2020)

Identifying Shared Risk Genes for Asthma, Hay Fever, and Eczema by Multi-Trait and Multiomic Association Analyses
por: Guo, Hongping, et al.
Publicado: (2020)

A genome-wide association study finds genetic variants associated with neck or shoulder pain in UK Biobank
por: Meng, Weihua, et al.
Publicado: (2020)

Seven newly identified loci for autoimmune thyroid disease
por: Cooper, Jason D., et al.
Publicado: (2012)

Subspecialization within default mode nodes characterized in 10,000 UK Biobank participants
por: Kernbach, Julius M., et al.
Publicado: (2018)

APOE2 AND AGING-RELATED OUTCOMES IN 261,000 UK BIOBANK OLDER ADULTS
por: Kuo, Chia-Ling, et al.
Publicado: (2019)

Anxiety and Depression in People with Eczema or Psoriasis: A Comparison of Associations in UK Biobank and Linked Primary Care Data
por: Matthewman, Julian, et al.
Publicado: (2023)

Genome-Wide Association Analysis of Over 170,000 Individuals from the UK Biobank Identifies Seven Loci Associated with Dietary Approaches to Stop Hypertension (DASH) Diet
por: Mompeo, Olatz, et al.
Publicado: (2022)

Twenty-eight genetic loci associated with ST-T-wave amplitudes of the electrocardiogram
por: Verweij, Niek, et al.
Publicado: (2016)

Discovery of novel heart rate-associated loci using the Exome Chip
por: van den Berg, Marten E., et al.
Publicado: (2017)

Combined analysis of keratinocyte cancers identifies novel genome-wide loci
por: Liyanage, Upekha E, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_j6bpj7lp35m2v5p2fc56320cm4