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Development of elastin-like polypeptide for targeted specific gene delivery in vivo
BACKGROUND: The successful deliveries of siRNA depend on their stabilities under physiological conditions because greater in vivo stability enhances cellular uptake and enables endosomal escape. Viral-based systems appears as most efficient approaches for gene delivery but often compromised in terms...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6969399/ https://www.ncbi.nlm.nih.gov/pubmed/31952530 http://dx.doi.org/10.1186/s12951-020-0574-z |