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Direct visualization of degradation microcompartments at the ER membrane

To promote the biochemical reactions of life, cells can compartmentalize molecular interaction partners together within separated non–membrane-bound regions. It is unknown whether this strategy is used to facilitate protein degradation at specific locations within the cell. Leveraging in situ cryo-e...

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Detalles Bibliográficos
Autores principales: Albert, Sahradha, Wietrzynski, Wojciech, Lee, Chia-Wei, Schaffer, Miroslava, Beck, Florian, Schuller, Jan M., Salomé, Patrice A., Plitzko, Jürgen M., Baumeister, Wolfgang, Engel, Benjamin D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6969544/
https://www.ncbi.nlm.nih.gov/pubmed/31882451
http://dx.doi.org/10.1073/pnas.1905641117