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ASH2L-Promoted HOXC8 Gene Expression Plays a Role in Mixed Lineage Leukemia-Rearranged Acute Leukemia

BACKGROUND: Mixed lineage leukemia (MLL) fusion protein alone exhibits poor histone lysine methyltransferase (HKMT) activity in catalyzing histone H3 Lys4 trimethylation (H3K4me3) in MLL-rearranged acute leukemia. METHODS: To explore the HKMT effect of another regulatory protein within the complex o...

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Detalles Bibliográficos
Autores principales:	Wu, Yu-Jie, Li, Li-xia, Liu, Lu, Zhao, Si-shu, Qiu, Hai-rong, Wang, Hui
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2020
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6969701/ https://www.ncbi.nlm.nih.gov/pubmed/32021283 http://dx.doi.org/10.2147/OTT.S221643

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