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High Molecular Weight Chitosan-Complexed RNA Nanoadjuvant for Effective Cancer Immunotherapy

Nucleic acid-based adjuvants have recently emerged as promising candidates for use in cancer vaccines to induce tumor-suppressing immune cells. In this study, we tested whether complexation of a nucleic acid-based adjuvant with chitosan (CTS) modulates immune adjuvant functions. As a nucleic acid-ba...

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Detalles Bibliográficos
Autores principales: Choi, Jin Joo, Le, Quoc-Viet, Kim, Dongho, Kim, Young Bong, Shim, Gayong, Oh, Yu-Kyoung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6969902/
https://www.ncbi.nlm.nih.gov/pubmed/31847372
http://dx.doi.org/10.3390/pharmaceutics11120680