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The 1,10-Phenanthroline Ligand Enhances the Antiproliferative Activity of DNA-Intercalating Thiourea-Pd(II) and -Pt(II) Complexes Against Cisplatin-Sensitive and -Resistant Human Ovarian Cancer Cell Lines

Ovarian cancer is the most lethal gynecological malignancy, often because of the frequent insurgence of chemoresistance to the drugs currently used. Thus, new therapeutical agents are needed. We tested the toxicity of 16 new DNA-intercalating agents to cisplatin (cDDP)-sensitive human ovarian carcin...

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Detalles Bibliográficos
Autores principales: Marverti, Gaetano, Gozzi, Gaia, Lauriola, Angela, Ponterini, Glauco, Belluti, Silvia, Imbriano, Carol, Costi, Maria Paola, D’Arca, Domenico
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6969938/
https://www.ncbi.nlm.nih.gov/pubmed/31817267
http://dx.doi.org/10.3390/ijms20246122

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