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Patterns of germline and somatic mutations in 16 genes associated with mismatch repair function or containing tandem repeat sequences
BACKGROUND: We assumed that targeted next‐generation sequencing (NGS) of mismatch repair‐associated genes could improve the detection of driving mutations in colorectal cancers (CRC) with microsatellite instability (MSI) and microsatellite alterations at selected tetranucleotide repeats (EMAST) and...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6970039/ https://www.ncbi.nlm.nih.gov/pubmed/31769227 http://dx.doi.org/10.1002/cam4.2702 |