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2-Methylquinazoline derivative 23BB as a highly selective histone deacetylase 6 inhibitor alleviated cisplatin-induced acute kidney injury

Histone deacetylases 6 (HDAC6) has been reported to be involved in the pathogenesis of cisplatin-induced acute kidney injury (AKI). Selective inhibition of HDAC6 might be a potential treatment for AKI. In our previous study, a highly selective HDAC6 inhibitor (HDAC6i) 23BB effectively protected agai...

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Detalles Bibliográficos
Autores principales: Hao, Yan, Guo, Fan, Huang, Zhuo, Feng, Yuying, Xia, Zijing, Liu, Jing, Li, Lingzhi, Huang, Rongshuang, Lin, Lin, Ma, Liang, Fu, Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6970081/
https://www.ncbi.nlm.nih.gov/pubmed/31894849
http://dx.doi.org/10.1042/BSR20191538