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OptFill: A Tool for Infeasible Cycle-Free Gapfilling of Stoichiometric Metabolic Models

Stoichiometric metabolic modeling, particularly genome-scale models (GSMs), is now an indispensable tool for systems biology. The model reconstruction process typically involves collecting information from public databases; however, incomplete systems knowledge leaves gaps in any reconstruction. Cur...

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Detalles Bibliográficos
Autores principales: Schroeder, Wheaton L., Saha, Rajib
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6970165/
https://www.ncbi.nlm.nih.gov/pubmed/31954977
http://dx.doi.org/10.1016/j.isci.2019.100783