Effect of long-acting β-agonists/glucocorticoids on human airway epithelial cell cytokine, transcriptomic and oxidative stress responses to cannabis smoke

LABA/GC intervention in airway epithelial cells exposed to cannabis smoke reduces levels of pro-inflammatory (CXCL8) and antiviral (CXCL10) mediators, while transcriptomic signatures of neutrophil-mediated immunity and oxidative stress remain elevated http://bit.ly/2qiSQhH

Detalles Bibliográficos
Autores principales: Huff, Ryan D., Aguiar, Jennifer A., Tse, Wayne, Stämpfli, Martin R., McConkey, Brendan J., Doxey, Andrew C., Hirota, Jeremy A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: European Respiratory Society 2020
Materias:
Original Research Letters
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6970181/
https://www.ncbi.nlm.nih.gov/pubmed/31984210
http://dx.doi.org/10.1183/23120541.00265-2019
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author Huff, Ryan D.
Aguiar, Jennifer A.
Tse, Wayne
Stämpfli, Martin R.
McConkey, Brendan J.
Doxey, Andrew C.
Hirota, Jeremy A.
author_facet Huff, Ryan D.
Aguiar, Jennifer A.
Tse, Wayne
Stämpfli, Martin R.
McConkey, Brendan J.
Doxey, Andrew C.
Hirota, Jeremy A.
author_sort Huff, Ryan D.
collection PubMed
description LABA/GC intervention in airway epithelial cells exposed to cannabis smoke reduces levels of pro-inflammatory (CXCL8) and antiviral (CXCL10) mediators, while transcriptomic signatures of neutrophil-mediated immunity and oxidative stress remain elevated http://bit.ly/2qiSQhH
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spelling pubmed-69701812020-01-24 Effect of long-acting β-agonists/glucocorticoids on human airway epithelial cell cytokine, transcriptomic and oxidative stress responses to cannabis smoke Huff, Ryan D. Aguiar, Jennifer A. Tse, Wayne Stämpfli, Martin R. McConkey, Brendan J. Doxey, Andrew C. Hirota, Jeremy A. ERJ Open Res Original Research Letters LABA/GC intervention in airway epithelial cells exposed to cannabis smoke reduces levels of pro-inflammatory (CXCL8) and antiviral (CXCL10) mediators, while transcriptomic signatures of neutrophil-mediated immunity and oxidative stress remain elevated http://bit.ly/2qiSQhH European Respiratory Society 2020-01-20 /pmc/articles/PMC6970181/ /pubmed/31984210 http://dx.doi.org/10.1183/23120541.00265-2019 Text en Copyright ©ERS 2020 http://creativecommons.org/licenses/by-nc/4.0/This article is open access and distributed under the terms of the Creative Commons Attribution Non-Commercial Licence 4.0.
spellingShingle Original Research Letters
Huff, Ryan D.
Aguiar, Jennifer A.
Tse, Wayne
Stämpfli, Martin R.
McConkey, Brendan J.
Doxey, Andrew C.
Hirota, Jeremy A.
Effect of long-acting β-agonists/glucocorticoids on human airway epithelial cell cytokine, transcriptomic and oxidative stress responses to cannabis smoke
title Effect of long-acting β-agonists/glucocorticoids on human airway epithelial cell cytokine, transcriptomic and oxidative stress responses to cannabis smoke
title_full Effect of long-acting β-agonists/glucocorticoids on human airway epithelial cell cytokine, transcriptomic and oxidative stress responses to cannabis smoke
title_fullStr Effect of long-acting β-agonists/glucocorticoids on human airway epithelial cell cytokine, transcriptomic and oxidative stress responses to cannabis smoke
title_full_unstemmed Effect of long-acting β-agonists/glucocorticoids on human airway epithelial cell cytokine, transcriptomic and oxidative stress responses to cannabis smoke
title_short Effect of long-acting β-agonists/glucocorticoids on human airway epithelial cell cytokine, transcriptomic and oxidative stress responses to cannabis smoke
title_sort effect of long-acting β-agonists/glucocorticoids on human airway epithelial cell cytokine, transcriptomic and oxidative stress responses to cannabis smoke
topic Original Research Letters
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6970181/
https://www.ncbi.nlm.nih.gov/pubmed/31984210
http://dx.doi.org/10.1183/23120541.00265-2019
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