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Distinct Immunological Landscapes Characterize Inherited and Sporadic Mismatch Repair Deficient Endometrial Cancer

Around 30% of endometrial cancers (EC) are mismatch repair (MMR) deficient, mostly as a consequence of mutations acquired during tumorigenesis, but a significant minority is caused by Lynch syndrome (LS). This inherited cancer predisposition syndrome primes an anti-cancer immune response, even in he...

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Detalles Bibliográficos
Autores principales:	Ramchander, Neal C., Ryan, Neil A. J., Walker, Thomas D. J., Harries, Lauren, Bolton, James, Bosse, Tjalling, Evans, D. G., Crosbie, Emma J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6970202/ https://www.ncbi.nlm.nih.gov/pubmed/31998307 http://dx.doi.org/10.3389/fimmu.2019.03023

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