Are we underutilizing bone marrow and cord blood? Review of their role and potential in the era of cellular therapies

Since the first hematopoietic stem cell transplant, over a million transplants have been performed worldwide. In the last decade, the transplant field has witnessed a progressive decline in bone marrow and cord blood utilization and a parallel increase in peripheral blood as a source of stem cells....

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Detalles Bibliográficos
Autores principales: Xue, Elisabetta, Milano, Filippo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: F1000 Research Limited 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6970216/
https://www.ncbi.nlm.nih.gov/pubmed/31984133
http://dx.doi.org/10.12688/f1000research.20605.1
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author Xue, Elisabetta
Milano, Filippo
author_facet Xue, Elisabetta
Milano, Filippo
author_sort Xue, Elisabetta
collection PubMed
description Since the first hematopoietic stem cell transplant, over a million transplants have been performed worldwide. In the last decade, the transplant field has witnessed a progressive decline in bone marrow and cord blood utilization and a parallel increase in peripheral blood as a source of stem cells. Herein, we review the use of bone marrow and cord blood in the hematopoietic stem cell transplant setting, and we describe the recent advances made in different medical fields using cells derived from cord blood and bone marrow.
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spelling pubmed-69702162020-01-24 Are we underutilizing bone marrow and cord blood? Review of their role and potential in the era of cellular therapies Xue, Elisabetta Milano, Filippo F1000Res Review Since the first hematopoietic stem cell transplant, over a million transplants have been performed worldwide. In the last decade, the transplant field has witnessed a progressive decline in bone marrow and cord blood utilization and a parallel increase in peripheral blood as a source of stem cells. Herein, we review the use of bone marrow and cord blood in the hematopoietic stem cell transplant setting, and we describe the recent advances made in different medical fields using cells derived from cord blood and bone marrow. F1000 Research Limited 2020-01-17 /pmc/articles/PMC6970216/ /pubmed/31984133 http://dx.doi.org/10.12688/f1000research.20605.1 Text en Copyright: © 2020 Xue E and Milano F http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review
Xue, Elisabetta
Milano, Filippo
Are we underutilizing bone marrow and cord blood? Review of their role and potential in the era of cellular therapies
title Are we underutilizing bone marrow and cord blood? Review of their role and potential in the era of cellular therapies
title_full Are we underutilizing bone marrow and cord blood? Review of their role and potential in the era of cellular therapies
title_fullStr Are we underutilizing bone marrow and cord blood? Review of their role and potential in the era of cellular therapies
title_full_unstemmed Are we underutilizing bone marrow and cord blood? Review of their role and potential in the era of cellular therapies
title_short Are we underutilizing bone marrow and cord blood? Review of their role and potential in the era of cellular therapies
title_sort are we underutilizing bone marrow and cord blood? review of their role and potential in the era of cellular therapies
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6970216/
https://www.ncbi.nlm.nih.gov/pubmed/31984133
http://dx.doi.org/10.12688/f1000research.20605.1
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