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The interplay between redox signalling and proteostasis in neurodegeneration: In vivo effects of a mitochondria-targeted antioxidant in Huntington's disease mice
Abnormal protein homeostasis (proteostasis), dysfunctional mitochondria, and aberrant redox signalling are often associated in neurodegenerative disorders, such as Huntington's (HD), Alzheimer's and Parkinson's diseases. It remains incompletely understood, however, how changes in redo...
Autores principales: | Pinho, Brígida R., Duarte, Ana I., Canas, Paula M., Moreira, Paula I., Murphy, Michael P., Oliveira, Jorge M.A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6970224/ https://www.ncbi.nlm.nih.gov/pubmed/31751762 http://dx.doi.org/10.1016/j.freeradbiomed.2019.11.021 |
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