Do Asian Patients Require Only Half of the Clozapine Dose Prescribed for Caucasians? A Critical Overview

Since 1997, studies have found that Asians need lower clozapine doses than Caucasians. Caucasians with average clozapine metabolism may need from 300 to 600 mg/day to reach the therapeutic range (350 ng/ml). Thus, serum clozapine concentration-to-dose (C/D) ratios typically range between 0.60 (male...

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Detalles Bibliográficos
Autores principales: de Leon, Jose, Rajkumar, Anto P., Kaithi, Arun R., Schoretsanitis, Georgios, Kane, John M., Wang, Chuan-Yue, Tang, Yi-Lang, Lin, Shih-Ku, Hong, Kyung Sue, Farooq, Saeed, Ng, Chee H., Ruan, Can-Jun, Andrade, Chittaranjan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2020
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6970303/
https://www.ncbi.nlm.nih.gov/pubmed/31997860
http://dx.doi.org/10.4103/IJPSYM.IJPSYM_379_19

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6970303/
https://www.ncbi.nlm.nih.gov/pubmed/31997860
http://dx.doi.org/10.4103/IJPSYM.IJPSYM_379_19

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