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Do Asian Patients Require Only Half of the Clozapine Dose Prescribed for Caucasians? A Critical Overview
Since 1997, studies have found that Asians need lower clozapine doses than Caucasians. Caucasians with average clozapine metabolism may need from 300 to 600 mg/day to reach the therapeutic range (350 ng/ml). Thus, serum clozapine concentration-to-dose (C/D) ratios typically range between 0.60 (male...
Autores principales: | de Leon, Jose, Rajkumar, Anto P., Kaithi, Arun R., Schoretsanitis, Georgios, Kane, John M., Wang, Chuan-Yue, Tang, Yi-Lang, Lin, Shih-Ku, Hong, Kyung Sue, Farooq, Saeed, Ng, Chee H., Ruan, Can-Jun, Andrade, Chittaranjan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wolters Kluwer - Medknow
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6970303/ https://www.ncbi.nlm.nih.gov/pubmed/31997860 http://dx.doi.org/10.4103/IJPSYM.IJPSYM_379_19 |
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