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Depotentiation depends on IP(3) receptor activation sustained by synaptic inputs after LTP induction
In CA1 neurons of guinea pig hippocampal slices, long-term potentiation (LTP) was induced in field excitatory postsynaptic potentials (EPSPs) or population spikes (PSs) by the delivery of high-frequency stimulation (HFS, 100 pulses at 100 Hz) to CA1 synapses, and was reversed by the delivery of a tr...
Autores principales: | Fujii, Satoshi, Yamazaki, Yoshihiko, Goto, Jun-ichi, Fujiwara, Hiroki, Mikoshiba, Katsuhiko |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2020
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6970427/ https://www.ncbi.nlm.nih.gov/pubmed/31949037 http://dx.doi.org/10.1101/lm.050344.119 |
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