Distribution of Bacterial α1,3-Galactosyltransferase Genes in the Human Gut Microbiome

Because of a loss-of-function mutation in the GGTA1 gene, humans are unable to synthetize α1,3-Galactose (Gal) decorated glycans and develop high levels of circulating anti-α1,3-Galactose antibodies (anti-Gal Abs). Anti-Gal Abs have been identified as a major obstacle of organ xenotransplantation an...

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Detalles Bibliográficos
Autores principales: Montassier, Emmanuel, Al-Ghalith, Gabriel A., Mathé, Camille, Le Bastard, Quentin, Douillard, Venceslas, Garnier, Abel, Guimon, Rémi, Raimondeau, Bastien, Touchefeu, Yann, Duchalais, Emilie, Vince, Nicolas, Limou, Sophie, Gourraud, Pierre-Antoine, Laplaud, David A., Nicot, Arnaud B., Soulillou, Jean-Paul, Berthelot, Laureline
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6970434/
https://www.ncbi.nlm.nih.gov/pubmed/31998300
http://dx.doi.org/10.3389/fimmu.2019.03000

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