Allopregnanolone Modulates GABAAR-Dependent CaMKIIδ3 and BDNF to Protect SH-SY5Y Cells Against 6-OHDA-Induced Damage

Allopregnanolone (APα), as a functional neurosteroid, exhibits the neuroprotective effect on neurodegenerative diseases such as Parkinson’s disease (PD) through γ-aminobutyric acid A receptor (GABAAR), but it has not been completely understood about its molecular mechanisms. In order to investigate...

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Detalles Bibliográficos
Autores principales: Wang, Tongtong, Ye, Xin, Bian, Wei, Chen, Zhichi, Du, Juanjuan, Li, Mengyi, Zhou, Peng, Cui, Huairui, Ding, Yu-Qiang, Qi, Shuangshuang, Liao, Min, Sun, Chenyou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Cellular Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6970471/
https://www.ncbi.nlm.nih.gov/pubmed/31998078
http://dx.doi.org/10.3389/fncel.2019.00569

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6970471/
https://www.ncbi.nlm.nih.gov/pubmed/31998078
http://dx.doi.org/10.3389/fncel.2019.00569

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